The influence of social adversity on cardiovascular aging

Cardiovascular disease (CV) is a leading global cause of death, primarily linked to aging, but influenced by various factors like inactivity, poor diet, and limited healthcare access. Social adversities, such as social isolation and challenging childhoods, also significantly impact CV health, weakening the immune system and altering genes. Understanding how social challenges affect CV health is complex, especially in humans due to overlapping risk factors. Rhesus macaques, with similar biological and social traits, offer a valuable translational model. This project at the Caribbean Primate Research Centre aims to explore the impact of social adversity on CV disease. Combining comprehensive CV health data with social metrics and physiological stress markers, the study seeks to uncover the biological mechanisms involved. By investigating the relationship between life challenges and CV disease, the research promises insights into safeguarding CV health amidst social adversity, potentially informing strategies for human health protection.

Faculty Supervisor:

Robert Shave

Student:

Partner:

Arizona State University

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology

University:

The University of British Columbia - Okanagan

Program: