Understanding signal drift in electrochemical aptamer-based sensors to achieve long-term continuous biomonitoring

This project aims to improve electrochemical aptamer-based sensors, that can monitor important biomolecules in real time, directly inside the body or in other complex environments. These sensors are promising because they can be adapted to detect many different targets, but their use is limited by a gradual loss of stability and performance over time. To solve this, we will develop a new method, called “strip-amplify,” that uses molecular techniques to better understand how and why these sensors break down. This knowledge will help create more durable sensors that can work for weeks or even months. The participating institutions will benefit by advancing cutting-edge sensor technology, improving tools for medical research, diagnostics, and industrial applications.

Faculty Supervisor:

Phillippe Dauphin Ducharme

Student:

Partner:

Eindhoven University of Technology

Discipline:

Life Sciences

Sector:

Education

University:

Université de Sherbrooke

Program: