Use of microfluidic platform to generate perfusable vessels for the study of transendothelial hormone flux

The challenges faced by mammals in adapting to their environment must be tightly controlled in order to ensure optimal body function. Hormones can travel in the bloodstream to reach various parts of the body and execute their biological actions on various organs. However, to reach their target the hormones must leave the bloodstream. That means they must cross the wall of blood vessels. This research project will use an integrated approach to examine the ways in which hormones leave the bloodstream and move to target tissues. Specifically, we will focus on iron as a nutritional cue for biological changes. In summary, this research will uncover and establish important new knowledge for animal physiologists.

Faculty Supervisor:

Gary Sweeney

Student:

Partner:

Korea Advanced Institute of Science and Technology

Discipline:

Life Sciences

Sector:

Life Sciences (not health); Biotechnology; Pharmaceuticals

University:

York University

Program: