The first successful clinical application of nanotechnology was the use of a nanoparticle container to deliver a drug to a tumour. That basic strategy of using a nanoparticle to carry a treatment or indicator molecule has a lot of potential, but requires continued research to determine the therapeutic effectiveness and potential toxicity of each container […]

Attention problems are common with aging and related disorders (like stroke) and are associated with poor recovery and quality of life. Many clinical tests of attention are not based on neurocognitive concepts and are limited to in person visits. The Dalhousie Computerized Attention Battery (DalCAB) is a theory-based, in-depth measure of attention that can be […]

Wide-Complex Tachyarrhythmia (WCT) is an abnormality in which the heart rate is elevated and QRS complex duration is increased. An electrocardiogram (ECG) is a simple and quick test used to review heart functioning, so ECG images can be used to determine whether a patient is having an abnormal heart rhythm such as WCT. A WCT […]

One of the biggest challenges of understanding the marine environment is that most species spend virtually all of their time underwater where they are difficult to count and monitor. Seabirds, as a top marine predator that feed on small forage fish, many of which are important to fisheries (e.g., herring), provide an alternative to underwater […]

Community- based Physiotherapy, Occupational Therapy, and Speech Therapy for children and youth with support needs is delivered by non-profit agencies across BC that do not have access to resources and supports to ensure they are providing evidence-based practice. This research project will help the partner organization, BCACDI, understand how it can implement a system to […]

Multidrug-resistant (MDR) bacterial pathogens are ubiquitous in hospitals and community settings. New antibiotics against unexploited targets are urgently needed to better control such infections. The proposed research aims to identify novel, drug targets and therapeutics for antibiotic-resistant nosocomial pathogens, capitalizing on a proprietary indel-targeting approach that takes advantage of structural differences between homologous essential human […]

Irving Oil Ltd. (IOL) manages impounded wetlands on company owned properties including a wetland located on the Little River at the site of the Saint John Oil Refinery. IOL in partnership with Ducks Unlimited Canada (DUC) manages this wetland and other impoundments to provide proper habitat for wildlife including fishes and ducks. To do this […]

Corticotropin-releasing factor (CRF) is a chemical found naturally in the brain that plays a key role in the mammalian stress response. CRF is also known to be involved in anxiety and mood disorders, as well as in various aspects of drug dependence, including long-term relapse to drug use. The teneurin C-terminal associated peptides (TCAP) comprise […]

This project will involve research into the optimal production and purification methods for bacteriophages that are effective against bacterial infections in pigs. Cytophage’s bacteriophages will provide a highly effective, environmentally safe, and a cost competitive alternative to antibiotics in the pork industry. This project will benefit Cytophage by helping to advance our technology and product […]

Emerging therapeutic agents that function through the brain’s neurotransmitter systems have recently shown robust benefits in a number of otherwise challenging to treat neurological conditions including depression and post-traumatic stress disorder. The long-term changes that these agents induce within neural tissue is still however unclear. This MITSCS program aims to to use expertise in tissue […]

The therapeutic potential of cannabinoids is well established. The study of these molecules is primarily based on their availability from the cannabis plant (Cannabis sativa). In addition to common cannabinoids, there are dozens of rare cannabinoids produced in C. sativa with potential therapeutic benefits that cannot be fully evaluated because of their scarcity. Thus, there […]

Osteoarthritis is the most common form of joint disease affecting over 80% of the human population above 75 years old and burdening health organizations worldwide. Osteoarthritis is characterized by progressive joint degeneration resulting in chronic pain and loss of joint function. Currently there is no cure for osteoarthritis; available treatments are only symptomatic targeting pain […]