A Longitudinal Comparison of Aripiprazole Vs. HigherMetabolic Risk Antipsychotic Drugs on Adiposity Using MRI

Antipsychotic medication is associated with metabolic abnormalities, including weight gain, an imbalance between glucose and insulin actions, and higher than normal lipid content. In particular, adolescent psychiatric patients are at increased risk for Type II Diabetes and cardiovascular disease when undergoing therapeutic treatment. Current analysis indicates that antipsychotic drugs have differing effects on body weight […]

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Development of a Rapid Point of Care (POC) test for Food and Water Safety

The project involves the development of a rapid detection test kit that will enable food processors to measure the absence or presence of potentially harmful pathogenic organisms prior to shipment to the general trade. The interns’ main objectives will be to dramatically reduce the assessment time for the tester- currently ranging from 4 to 5 […]

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Long-term Monitoring Protocol and Analysis Template for American Eel (Anguilla rostrata)

In 2012, the American Eel were recommended by the Committee on the Status of Endangered Wildlife in Canada to be upgraded to Threatened from Special Concern. American Eel are important to Aboriginal people, and recreational and commercial fishers. Research from a four-year-study (2009-2012) occurring in a near pristine watershed, looked at habitat selection and population […]

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Targeting the ubiquitin system function through GID4 – Year two

Protein turnover is an incompletely understood aspect of biology, important for various processes including adaption to environmental stimuli. Over 500 protein complexes (E3 ligases) are involved in marking proteins for degradation, but only a small number of these E3 ligases are well characterised. The current project seeks to develop chemical inhibitors of GID4—a key component […]

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The importance of nutrition for ice hockey players

One aspect of hockey science that remains elusive is the role of nutrition in performance. We propose to study the dietary intake of hockey players and also examine their nutritional knowledge with a questionnaire. We will also examine the nutritional knowledge of athletic trainers and examine the role that they play from a nutritional point […]

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Valorisation de biomasses marines et subjectivation d’ingrédients bioactifs

À l’échelle mondiale, le nombre de personne atteintes de désordres métaboliques associés à l’obésité ne cesse de progresser malgré les traitements disponibles. En parallèle, les industries agroalimentaires au Québec cherchent à valoriser des composés résiduels issus de leur production dont les propriétés thérapeutiques restent souvent inexploitées. Par conséquent, l’objectif de ce projet, en partenariat avec […]

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Valorisation de biomasses marines et subjectivation d’ingrédients bioactifs – Year two

À l’échelle mondiale, le nombre de personne atteintes de désordres métaboliques associés à l’obésité ne cesse de progresser malgré les traitements disponibles. En parallèle, les industries agroalimentaires au Québec cherchent à valoriser des composés résiduels issus de leur production dont les propriétés thérapeutiques restent souvent inexploitées. Par conséquent, l’objectif de ce projet, en partenariat avec […]

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MRI Estimates of Repeated Demyelination and Tissue Injury as Markers of Progressive Multiple Sclerosis

Multiple Sclerosis (MS) can be divided into three clinical phenotypes: relapsing remitting (RRMS), secondary progressive (SPMS) and primary progressive (PPMS). RRMS is characterized by episodic worsening followed by full or partial recovery, whereas SPMS and PPMS are characterized by steady accrual of disability. Progressive MS remains poorly understood and generally fails to respond to therapies […]

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MRI Estimates of Repeated Demyelination and Tissue Injury as Markers of Progressive Multiple Sclerosis – Year two

Multiple Sclerosis (MS) can be divided into three clinical phenotypes: relapsing remitting (RRMS), secondary progressive (SPMS) and primary progressive (PPMS). RRMS is characterized by episodic worsening followed by full or partial recovery, whereas SPMS and PPMS are characterized by steady accrual of disability. Progressive MS remains poorly understood and generally fails to respond to therapies […]

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Targeting the ubiquitin system function through GID4

Protein turnover is an incompletely understood aspect of biology, important for various processes including adaption to environmental stimuli. Over 500 protein complexes (E3 ligases) are involved in marking proteins for degradation, but only a small number of these E3 ligases are well characterised. The current project seeks to develop chemical inhibitors of GID4—a key component […]

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