Safety and effectiveness of Mifegymiso® offered through different service delivery points: a national prospective cohort study

Medication abortion with mifepristone and misoprostol has the potential to advance women’s access to safe and geographically accessible abortion care. Improved access to medication abortion protects women’s right to health and supports women’s autonomy and agency. However, the over-regulation of mifepristone in much of the Global North has muted the promise of this pill-based regimen […]

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Safety and effectiveness of Mifegymiso® offered through different service delivery points: a national prospective cohort study – Year two

Medication abortion with mifepristone and misoprostol has the potential to advance women’s access to safe and geographically accessible abortion care. Improved access to medication abortion protects women’s right to health and supports women’s autonomy and agency. However, the over-regulation of mifepristone in much of the Global North has muted the promise of this pill-based regimen […]

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Understanding the gaps in the adoption of animal care practices in Canada – Year two

Welfare issues such as lameness and body injuries (LBI) negatively impact health, productivity, and longevity of dairy cows. Despite research, regulatory and outreach efforts, the current prevalence of LBI is high in Canada and shows little evidence of improvement. The proposed study will use an integrated, structured approach to identify gaps influencing the adoption of […]

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Impact of microparticles in cancer progression

Blood platelets are the principal source of cells known to shed small extracellular vesicles which package biologically active molecules. We have recently identified a new type of these vesicles (called microparticles/MPs) that contain mitochondria, which represent the energy producing motors for living cells. We have also discovered that MPs preferentially bind and internalize into leukemia […]

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Impact of microparticles in cancer progression – Year two

Blood platelets are the principal source of cells known to shed small extracellular vesicles which package biologically active molecules. We have recently identified a new type of these vesicles (called microparticles/MPs) that contain mitochondria, which represent the energy producing motors for living cells. We have also discovered that MPs preferentially bind and internalize into leukemia […]

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Epigenetic Regulators of Anticancer Drug Response

The effectiveness of cancer drugs depends on several factors which are governed by the genetic and ‘epigenetic’ code of cancer cells. The epigenetic code comprises those heritable modifications that bookmark DNA and DNA-associated proteins to guide the expression of genetic attributes without changing the DNA sequence. This epigenetic code is written, read, and erased by […]

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Epigenetic Regulators of Anticancer Drug Response – Year two

The effectiveness of cancer drugs depends on several factors which are governed by the genetic and ‘epigenetic’ code of cancer cells. The epigenetic code comprises those heritable modifications that bookmark DNA and DNA-associated proteins to guide the expression of genetic attributes without changing the DNA sequence. This epigenetic code is written, read, and erased by […]

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Development of new methods for screening bioilogics by means of Capillary Electrophoresis (CE) coupled with Mass-Spectrometer (MS) via novel Open Port Probe Sampling Interface (OPP)

The methods for screening complex biological samples found wide application in pharmaceutics, forensic science and medical science. The majority of these methods involve several analytical techniques coupled together in order to maximize the efficiency of the analysis. For example, the combination of Capillary Electrophoresis (CE) with Mass Spectrometry (MS) creates a new analytical platform (CE-MS) […]

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Development of new methods for screening bioilogics by means of Capillary Electrophoresis (CE) coupled with Mass-Spectrometer (MS) via novel Open Port Probe Sampling Interface (OPP) – Year two

The methods for screening complex biological samples found wide application in pharmaceutics, forensic science and medical science. The majority of these methods involve several analytical techniques coupled together in order to maximize the efficiency of the analysis. For example, the combination of Capillary Electrophoresis (CE) with Mass Spectrometry (MS) creates a new analytical platform (CE-MS) […]

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Development, implementation and evaluation of a bulk tank milk surveillance program for infectious and emerging diseases on Ontario dairy farms

The spread of endemic and emerging infectious diseases continues to plague the dairy industry. The convergence of human, animal, and ecosystem interactions results in emergence and re-emergence of diseases in dairy cattle such as salmonellosis and anaplasmosis. Adding to the mix, frequent buying of cattle contributes to rapid dissemination of infectious diseases in dairy cattle. […]

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Hydrolysat de tissus intestinaux comme ingrédient actifs améliorant la transition au moment du sevrage chez le porcelet

L’utilisation des antibiotiques en productions animales reste une problématique importante malgré le développement d’alternatives et une meilleure connaissance de la santé digestive. Dans une optique de durabilité, les différents acteurs impliqués en productions animales ont travaillé à réduire l’utilisation des antibiotiques dans les aliments du bétail et de la volaille. Cette utilisation importante des antibiotiques […]

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Quantifying community-level responses to anthropogenic landscape disturbance and management using multi-array camera trap data

Habitat loss through anthropogenic landscape disturbance is one of the leading drivers of biodiversity loss, yet activities such as resource extraction and agriculture play a vital role in the global economy. Understanding impacts of such disturbances, through robust environmental monitoring protocols, is key to maintain a balance between economic growth and environmental sustainability. Cost-effective monitoring […]

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