Role of cannabinoids on fast-inactivation of cardiac Nav channels

Cannabinoids are natural products derived from the Cannabis sativa plant (commonly known as marijuana). Cannabidiol (CBD), the main non-psychotropic cannabinoid is reputed to have medicinal benefits and is approved for the treatment of two seizure disorders. Other non-psychotropic cannabinoids, like cannabinol and cannabigerol, are less studied. We previously found that CBD both directly and indirectly […]

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Role of cannabinoids on fast-inactivation of cardiac Nav channels – Year two

Cannabinoids are natural products derived from the Cannabis sativa plant (commonly known as marijuana). Cannabidiol (CBD), the main non-psychotropic cannabinoid is reputed to have medicinal benefits and is approved for the treatment of two seizure disorders. Other non-psychotropic cannabinoids, like cannabinol and cannabigerol, are less studied. We previously found that CBD both directly and indirectly […]

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Chemically upgradation and hybrid biocatalytic valorization of lignin into green aviation ligno-jet fuel and paraffinic hydrocarbons

‘Low-Carbon Fuels’ refer to fuels produced from biological and waste resources with lower lifecycle greenhouse gas emissions than fossil fuels. This project, supported by Suncor and performed at Ryerson University, aims to explore the use of innovative biocatalytic and catalytic processes to produce drop-in ligno-biojet fuel from lignin. A single biochemical step will be utilized […]

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Understanding the gaps in the adoption of animal care practices in Canada

Welfare issues such as lameness and body injuries (LBI) negatively impact health, productivity, and longevity of dairy cows. Despite research, regulatory and outreach efforts, the current prevalence of LBI is high in Canada and shows little evidence of improvement. The proposed study will use an integrated, structured approach to identify gaps influencing the adoption of […]

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Health benefits of living in a wellness-centred community

The general objective of this project is to test for improvements in the physiological and psychosocial health of residents in a wellness-centred community (e.g. the Wellness Suites) who engage in a prescribed healthy lifestyle that emphasizes regular exercise and a modified vegan (i.e. Pegan) diet. Physiological, molecular, and psychosocial assessments will be used to identify […]

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Evaluating synergism effects of selected plant extract compounds with metal-based antimicrobials for their antibacterial and anti-biofilm potency.

The progression of bacterial antimicrobials resistance (AMR) has led us to an era that urgently requires alternative antimicrobial therapies. Metal-based antimicrobials (MBA) are increasingly seen as part of the solution. Several metals are already extensively used to prevent and treatment of infections. Silver/copper ionizers are presently used to control pathogens in Canadian hospital water distributions […]

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Evaluating synergism effects of selected plant extract compounds with metal-based antimicrobials for their antibacterial and anti-biofilm potency – Year two

The progression of bacterial antimicrobials resistance (AMR) has led us to an era that urgently requires alternative antimicrobial therapies. Metal-based antimicrobials (MBA) are increasingly seen as part of the solution. Several metals are already extensively used to prevent and treatment of infections. Silver/copper ionizers are presently used to control pathogens in Canadian hospital water distributions […]

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Development of COVID-19 Rapid Diagnostic Test

The current workflow for COVID-19 testing is overwhelmed for many reasons including the need for time-consuming sample preparation, the limited availability of test reagent, and the length of time it takes to complete the test process (approximately 3 hours). As the test-and-trace approach is critical to containing the spread of this virus, rapid diagnostics are […]

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Using priority effects and soil amendments to optimize ecological restoration of the Fortis pipeline right-of-way – Year two

FortisBC proposes to replace a pipeline in Kamloops, B.C. Of concern are habitat losses, loss of native plant communities and alteration of the composition of plant communities due to introduction of invasive species. My research addresses the role of order of seed arrival, called priority effects, and soil amendments such as straw matting and wood […]

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Land capability modeling for the Canadian prairies towards ecosystem services offset protocols

Humanity faces the triple challenge of stabilizing climate, ensuring food security, and safeguarding nature. Innovative approaches for climate- and biodiversity-friendly agriculture capable of sustaining resilient production landscapes are urgently needed. Carbon markets offer a platform for market-driven solutions that incentivize soil carbon sequestration through nature-based solutions. Canada employs a cap-and-trade scheme for domestic carbon credit […]

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Land capability modeling for the Canadian prairies towards ecosystem services offset protocols – Year two

Humanity faces the triple challenge of stabilizing climate, ensuring food security, and safeguarding nature. Innovative approaches for climate- and biodiversity-friendly agriculture capable of sustaining resilient production landscapes are urgently needed. Carbon markets offer a platform for market-driven solutions that incentivize soil carbon sequestration through nature-based solutions. Canada employs a cap-and-trade scheme for domestic carbon credit […]

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