Efficacy and feasibility of online cognitive training platforms for older adults with subjective cognitive complaints: A randomized controlled trial

With an aging population on the rise, the prevalence of cognitive decline is expected to increase substantially. Goal Management Training® (GMT) and the Memory and Aging Program® (MAP) are cognitive interventions that have been studied extensively and applied clinically to address these needs. Although previous research has demonstrated efficacy of the in-person versions of both […]

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Genes to affordable medicines – Stream 1-A2

The Structural Genomics Consortium (SGC) is a not-for-profit public-private partnership research organization that aims to accelerate the discovery of new medicines through open science. This Mitacs cluster will bring together SGC’s industry and academic collaborators to work together towards new and affordable medicines for challenging diseases. Sixty-three post-doctoral fellows will spend 2-3 years developing open […]

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Genes to affordable medicines – Stream 1-B1

The Structural Genomics Consortium (SGC) is a not-for-profit public-private partnership research organization that aims to accelerate the discovery of new medicines through open science. This Mitacs cluster will bring together SGC’s industry and academic collaborators to work together towards new and affordable medicines for challenging diseases. Sixty-three post-doctoral fellows will spend 2-3 years developing open […]

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Prevention of noise- and cisplatin-inducedhearing loss by oral administration of theflavonoid-enriched fraction AF4 in mice

Flavonoids are polyphenolic compounds which give fruits and vegetables their bright colours. Habitual consumption of dietary flavonoids reduces the risk for neurodegenerative disorders such as Parkinson’s disease, stroke and Alzheimer’s disease. Pre-clinical studies performed using animal models for these disorders have convincingly demonstrated that flavonoids not only halt the pathological processes which cause neurodegeneration but […]

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Développement de substituts de terre végétale à partir de matériaux locaux pour la végétalisation de la mine Canadian Malartic

L’exploitation des mines à ciel ouvert entraine souvent un changement du paysage, des horizons et de la structure du sol. L’utilisation de matériaux peu coûteux disponibles sur les sites miniers et dans les environs constitue une alternative pour remédier à la problématique du manque de terre végétale nécessaire végétaliser les parcs à rejets miniers. Les […]

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Redesign of a commercial across-breed genetic evaluation system and in-silico investigations of resulting system performance and flexibility.

Genetic improvement is core to the long-term productivity and viability of all livestock industries. A review of crossbred genetic evaluation methods and approaches for national and international genetic improvement programs will determine the necessary improvements to make to AgSights’ genetic evaluation system (GES). Research will be conducted on hardware, software packages and statistical methods best […]

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Développement d’une méthode de segmentation et de reconstruction semi-automatique des structures hépatiques à partir d’images CT et IRM pour leur intégration dans la plateforme ORS Visual

La segmentation du foie est une demarche consistant a delimiter les contours de I’organe des les images medicales volumiques, telles que Ie CT-Scan et I’IRM, afin d’estimer son volume a des fins de planification preoperatoire. Cette operation, typiquement realisee manuellement par un technicien ou un radiologue, est une demarche fastidieuse qui requiert entre 45 et […]

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Modélisation de la coulée de l’érable à sucre à l’échelle de l’arbre

L’érable à sucre est exploité depuis plusieurs siècles en raison de la concentration particulièrement élevée en sucre de sa sève. Malgré son importance économique, notamment au Canada, les paramètres qui régulent le mécanisme de la coulée à l’échelle de l’arbre sont encore mal connus. Des études précédentes ont mise en évidence l’influence des nombreux paramètres […]

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Statistical perspectives on the use of pharmacovigilance data and electronic health records to verify predicted chemical hazards of drugs from in-vitro toxicological data

The liver is considered as one of the organs that are highly susceptible to drug-induced toxicity, leading to a diverse set of responses such as acute liver injuries, black-box warnings, and possible market withdrawal of medications in spite of having first appeared non-toxic and effective in animal and clinical studies. Over the last few decades, […]

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Investigating the Role of Novel Fatty Acid-Binding Protein (FABP) Inhibitors as Treatments for Anxiety Disorders

Anxiety disorders and chronic stress represent major healthcare and economic burdens worldwide. Approximately 75% of Canadians who use health services for a mental illness present with anxiety disorders which may affect up to 10% of the population in terms of lifetime occurrence. Despite the large prevalence of anxiety-related disorders in Canada, there are currently a […]

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