Biological sources and the persistence of aerosols generated by variousdental procedures

Dental personnel are high risk professions in contracting and disseminating COVID-19 due to their transmits through respiratory droplets, dental personnel are at high risk of being exposed to the virus if an asymptomatic patient comes to their clinic. However, limited studies have been performed on the characterization of aerosols generated during dental procedures, how far […]

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An improved pipeline for processing and analysis of facial surface images in medicine

This Mitacs proposal tackles several outstanding issues that must be addressed to complete development of a widely applicable pipeline for quantitative analysis of 3D facial shape in medicine. Here, we focus on specific applications of imaging pipelines in genetic syndrome diagnosis and facial surgery visualization and planning. The fellows will develop (a) cutting edge, deep […]

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Development of microneedle array patch for COVID-19 vaccine delivery

COVID-19 is a global pandemic with no effective therapeutic and preventive agents. Given the high infectivity of the SARS-CoV-2 and severity of the disease, vaccines are urgently needed to tackle the infection of this novel coronavirus. Thus far, various types of vaccine candidates, in different stages of preclinical testing and clinical trials, are being explored, […]

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Development of Prophylactic Therapy to Reduce COVID-19 Infections

Working with Avicanna Inc., a Canadian biopharmaceutical company with advanced natural cannabinoid solutions, we will develop an easy-to-use preventative treatment, in the form of a mouthwash and/or throat gargle product, for both clinical and at-home use. A critical step of the infection is when the virus enters human host cells, which is enabled by the […]

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Examination of a 90-day self-compassion journal

Individuals can view their failures or inadequacies through a self-critical, isolated lens or they can view it through a self-compassionate one. Whereas the self-critical lens can increase stress and negative feelings, viewing failures or inadequacies with self-compassion leads to better coping and greater well-being. Self-compassion journaling is a low-cost means of helping individuals to increase […]

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Evaluation of pollinator restoration and management in The Meadoway

The purpose of this project is to identify bees and evaluate plant-pollinator networks based on the biomonitoring surveys conducted at the Meadoway in 2020 in partnership with the Toronto and Region Conservation Authority (TRCA). The aim of these surveys is to develop a baseline understanding of bee diversity in the Meadoway and evaluate the impacts […]

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IL-1-dependent ncRNA-based-therapy approach to enhance the bioactivity of endothelial progenitor cells in ischemic retinopathy: a new vasoprotective strategy

Retinopathy of prematurity (ROP) is the leading cause of blindness in premature neonates. ROP is associated with inflammation largely mediated trough interleukin (IL-1), which triggers an initial critical phase of ocular vascular degeneration. ROP is also an excellent model of ischemic retinopathies in general. The formation of new blood vessels after tissue ischemia is not […]

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IL-1-dependent ncRNA-based-therapy approach to enhance the bioactivity of endothelial progenitor cells in ischemic retinopathy: a new vasoprotective strategy – Year two

Retinopathy of prematurity (ROP) is the leading cause of blindness in premature neonates. ROP is associated with inflammation largely mediated trough interleukin (IL-1), which triggers an initial critical phase of ocular vascular degeneration. ROP is also an excellent model of ischemic retinopathies in general. The formation of new blood vessels after tissue ischemia is not […]

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THE USE OF WEARABLE VITAL SIGNS SENSOR TECHNOLOGY FOR EARLY PHYSIOLOGICAL DETECTION AND TRACKING OF VIRAL RESPIRATORY TRACT INFECTIONS

BACKGROUND: Viral respiratory tract infection (VRTI) is the most common illness in humans, resulting in a total economic impact of $40 billion annually in the United States. Taking into consideration the current novel coronavirus pandemic – impacting billions of people around the world, compromising the global economy, and putting extreme pressure on healthcare systems – […]

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The Use Of Wearable Vital Signs Sensor Technology For Early Physiological Detection And Tracking Of Viral Respiratory Tract Infections – Year two

BACKGROUND: Viral respiratory tract infection (VRTI) is the most common illness in humans, resulting in a total economic impact of $40 billion annually in the United States. Taking into consideration the current novel coronavirus pandemic – impacting billions of people around the world, compromising the global economy, and putting extreme pressure on healthcare systems – […]

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