Using chemokines to enhance DC-based cell therapy

Immune therapies for cancer are in their early stages and require further investigation to improve their function. Chemokines and their receptors are responsible for directing white blood cells to various parts of the body. Because they are so important in controlling the immune response, they make ideal targets for therapy. To exploit this, we aim […]

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Cryoprotecant toxicity accumulation models in mollusc oocytes

Cryopreservation of aquatic species’ gametes and embryos would enable stable and sustainable resources for genetic management in species preservation and breedstock for aquaculture. Cryopreservation of oocytes and embryos is of considerable financial interest to both Spanish and Canadian aquaculture, yet there have been no industry-scale successes in their cryopreservation. The Paredes lab at the University […]

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Cannabis used for medical purposes by children in Canada

Cannabis products are being used for a variety of conditions. In Canada, there are no cannabis products approved for use in children. Without evidence from clinical trials doctors are hesitant to recommend cannabis products for children. In order for doctors to feel confident in advising parents on medical cannabis they need better information on if […]

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Breeding Waterfowl Use of Restored Wetlands in the Cariboo Region of British Columbia

The intern will be conducting surveys of breeding waterfowl at nine wetlands previously restored by Ducks Unlimited Canada. Wetlands provide abundant ecosystem services and are threatened by modification from environmentally damaging human activities that have reduced their quantity and function. Waterfowl are highly dependent on wetlands for many stages of their lifecycle and Ducks Unlimited […]

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Generating macrophages from cultured embryonic stem cells

Macrophages are a type of white blood cell of the immune system that engulfs and digests cellular debris, foreign substances, microbes and cancer cells in a process called phagocytosis. They are often involved in development of inflammation, but in some settings can have the opposite effect. Much research is dedicated to investigating how macrophages develop […]

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Sernova’s Cell Pouch SystemTM: next-generation preclinical development and assessment of engraftment efficiency in clinical islet transplantation

Next generation preclinical development (caspase inhibitors, stem cell evaluation) and islet metabolic engraftment efficiency in a Phase I/II clinical study of the Cell Pouch™ for islet transplantation in Type 1 diabetes. (The Cell Pouch System™ is a proprietary non-biodegradable polymer device designed by biologists, scientists and engineers which unobtrusively fits under the skin, rapidly incorporating […]

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Analyzing Agriculture and Biodiversity Trade-offs in Three Sub-Saharan Countries at the Watershed Scale

With the onset of climate change and an ever-increasing human population, Sub-Saharan Africa faces a three-pronged sustainable development dilemma: how to increase food security while also conserving biodiversity and reducing social inequality. Given the importance of agriculture in Sub-Saharan economies, agricultural intensification and expansion will likely comprise the main course of action to address food […]

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Characterising and assessing seabird bycatch in expanding Arctic fisheries

Fisheries are an important industry in Canada, particularly in rural communities that depend on marine resources for sustainable economic opportunities. But all fishing imposes environmental costs. In the case of northern fisheries, one cost of concern is the incidental bycatch of seabirds by fisheries. Birds, attracted to bait and discards from vessels, can get ensnared […]

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Fibrostenotic Crohn’s disease: Regulation of Fibrosis and inflammation with Cannabigerol and other cannabinoids

The goal of the project is to determine if the cannabis-derived, non-psychoactive compound, cannabigerol (CBG) (a key component of Cannabis), which is known to reduce inflammation in a mouse model of colon inflammation, can also prevent intestinal strictures (fibrosis) and narrowing of the intestine in the setting of intestinal inflammation. We will use cell culture […]

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An emerging aquatic invasive species in Saskatchewan: distribution and ecology of the Prussian carp

Invasive aquatic species are one of the largest threats to aquatic ecosystems and cost Canadians around $343 million annually. Aquatic invasive species negatively impacts recreational use of freshwater and can decrease water quality, reduce native populations, and can cause fisheries to collapse. Prussian carp are an invasive species native to Asia that have recently been […]

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Comprendre l’utilisation des services de santé des résidents de l’office municipal d’habitation de Trois-Rivières

L’Office municipal d’habitation de Trois-Rivières (OMHTR) est un organisme à but non lucratif dont la mission est d’aider les personnes et les familles à faible revenu à se loger convenablement. L’OMHTR a récemment mis en place une clinique communautaire de santé en partenariat avec l’Université du Québec à Trois-Rivières. Cette clinique ayant remporté un vif […]

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