The morphogenetic effects of DNA damage on the filamentous bacterium Streptomyces

Binary fission, the process in which one bacterium divides into two identical cells, is the most common form of bacterial cell division. However, not all bacteria grow like this. The Streptomyces are a filamentous bacterium that undergo a lifecycle (similar to eukaryotic fungi) which culminates in sporulation. The Streptomyces are a biomedically important bacterium as […]

Read More
New Inhibitors of HIV Infection

A new target on HIV gp120 for interventive drug therapy has been discovered and a company, ViroCarb, initiated to screen for small molecule inhibitors that bind in this site. Two structurally related inhibitors have been isolated from chemical libraries. This internship is to determine the scope of these inhibitors, whether they are able to inhibit […]

Read More
Development and application of molecular tools to assess the acute and chronic impacts of petroleum hydrocarbons on birds

The Northern Gateway Pipeline and similar projects propose to transport oil from Alberta to tidewater terminals in British Columbia and eastern Canada. Accidental release of petroleum distillates and related by-products would have consequences on the marine ecosystem. To evaluate spill implications for seabirds, we propose to develop and apply molecular tools to assess toxicological and […]

Read More
Management, host pathogenicity, and rapid identification of Magnaporthe poae, causal agent of summer patch on annual bluegrass and Kentucky bluegrass turf

This project is designed to determine best management practices for a devastating disease of turfgrass that is currently controlled primarily by multiple fungicide applications. By assessing appropriate cultural practices aimed at reducing disease development it is our hope that we can reduce fungicide applications for this disease. In addition, the development of a rapid and […]

Read More
Arctic-Nesting Bird Monitoring and the Impacts of Mining Disturbances

Agnico Eagle Mines Ltd. has proposed the Whale Tail Project, approximately 130km North of Baker Lake, NU. The project includes the construction a dyke within Whale Tail Lake that will divert water from the proposed mining pit into the surrounding lakes and tributaries, resulting in flooding that will elevate the water levels by 4 m […]

Read More
Palaeobiota of the mid-Cretaceous Burmese amber

Amber from Myanmar, or Burmese amber, is considered to be one of the most important deposits for studying mid-Cretaceous terrestrial biodiversity (99 million-years ago). Amber preserves specimens in three-dimensions with soft tissues, internal organs and integumentary structures. Vertebrate specimens in amber have proven valuable for studying various aspects of the anatomy, evolution and diversification of […]

Read More
Revitalizing Indigenous traditional management of salmon – evaluating risk, opportunities and needs for re-emergence of traditional terminal fisheries

First Nations have fished for salmon in British Columbia for more than 10,000 years. Traditionally, many First Nations fisheries were conducted using weirs – fences constructed in the river – or stone fish traps, and these traditional technologies were used for thousands of years to manage and harvest salmon. However, with the arrival of commercial […]

Read More
To Investigate the Role of Prohibitin-1 (PHB1) In the Functional Plasticity of Macrophage

Macrophages are a highly diverse cell type that plays crucial roles in the body such as fighting pathogens, maintaining self-tolerance, surveillancing early cancer cells and tissue repair, whereas dysregulation of these functions are often associated with diseases such as obesity, diabetes, cancers and autoimmune diseases. Up to date, factors that regulate the metabolic switches between […]

Read More
Metabolic and biochemical characterization of terpenoid profiles in the high-value plants hop (Humulus lupulus), tea tree (Melaleuca alternifolia), and cannabis (Cannabis sativa)

Despite advances in biotechnology and organic synthesis, plants remain the main source of many of high-value bioactive compounds used in the medical, fragrance and food industries. Increasing demand for bioactive plants (e.g., cannabis and extracts thereof) require robust authentication approaches to verify feedstock, identify product adulteration and ensure product safety for consumers. This research aims […]

Read More