Quantifying the economic co-benefits of conservation action in the Fraser River Estuary

Popular belief suggests that investing in conservation costs jobs and economic opportunities. This argument continues to be used to steer investment away from conservation and towards industries that exploit natural resources. Part of this argument originates from how we currently evaluate economic return on investment for conservation action. Current methods do not properly account for […]

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Investigation of the role of CDK10 in pancreatic cancer growth and metastasis

This collaboration between the Tai Lab at BC Cancer Agency and the biotechnology company STEMCELL will validate a 3D culturing system that supports the growth of normal and malignant pancreatic stem cells. Specifically, we hope to optimize the culturing condition for the growth media to ensure efficient and reproducible outcomes for pancreatic stem cells growing […]

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Revegetation of disturbed areas in Northern Manitoba

Revegetation of northern Manitoba ecosystems, disturbed by hydroelectric development, is critical to meet the ecological and cultural needs of the First Nation communities located in these areas. To establish a viable self-sustaining ecosystem, it is important to understand the challenges associated with reclamation in these disturbed areas. The main goal of our proposed research is […]

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Study of the Mechanism of Action of Fluorescence Biomodulation in Tissue Regeneration and Acceleration of Wound Healing

Fluorescence Biomodulation (FB) is a novel technology that employs fluorescence light energy (FLE) to positively impact the three phases of healing. In the clinical setting, FB has been demonstrated to be safe and effective in the management of both acute and chronic wounds, resulting in accelerated wound closure while reducing inflammation, bacterial growth, and pain. […]

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Variability in brain networks and cognitive performance across the lifespan

From infancy to old age, individuals experience massive changes in both behavior and brain function. The worldwide increase in human life expectancy along with population aging highlight the need to investigate and better understand the dynamic relationship between cognitive health and aging. In order to promote productivity, sustained sense of well-being and social engagement, and […]

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The enemy of my enemy is my friend: fear responses in mussels exposed to apex and meso-predators

Top-down control in ecosystems helps maintain ecosystem stability and resilience; however, anthropogenic stressors, such as commercial fishing, have led to the global decline of apex predators. There is a growing recognition that the indirect effects of predators on prey (eg. fear-mediated behavioural responses) could be just as important as direct consumption. For instance, apex predators […]

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Integrated post-harvest wash systems for fruit and vegetable decontamination for reducing water usage and decrease emission of disinfectant byproducts in wastewater streams

The Canadian Food Guide has recommended an increase in fresh produce in the daily diet. Although the nutritional benefits of fresh produce are well established there are continuing food safety issues, high wastage and water consumption. To enhance safety and shelf-life it is common practice to pass produce through a post-harvest wash using chlorine as […]

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Influences of Stress on GnIH Expression in Bats

In 2000 a novel protein, referred to as GnIH, was discovered to inhibited the release of reproductive regulating hormones in the brain of quail. Since then, GnIH has identified in all studied vertebrate including fish, amphibians, and mammals. It has been shown to decrease hormone synthesis, be produced and act in reproductive tissues, as well […]

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Calcium Supplements, Elemental Bioavailability, and Uptake by Bone

The goal of this Mitacs research proposal is to develop and apply experimental methodology capable of distinguishing the influence of calcium supplement dosage form upon elemental calcium uptake, plasma concentration and spatial distribution in the bone of laboratory rats. In order to achieve those endpoints, we plan to utilize the compound strontium ranelate, which serves […]

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Generation of S9 from fish cell lines as an alternative to live animals

Live animal testing is currently the standard approach for assessing the risk chemicals may pose to wildlife. The costs and ethical concerns associated with live animal testing, however, constitute a significant challenge to regulators and industry in fulfilling their testing mandates to characterize the risks of environmental contaminants. To reduce these challenges, improved exposure assessments […]

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Baseline Carbon Stocks in Nova Scotia Forests: Role of the Forest Floor

The forWater Network, funded by the federal government as well as industry partners and provincial governments, is a national research network looking into the impacts of forest-management strategies on drinking-water source quality and treatability. forWater Network researchers at Dalhousie University (including Duinker, the supervisor in this application) are working with Halifax Water and Westfor Management […]

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A mechanistic study of the association between poverty and executive functions in early childhood: Contributions of early brain development and the early caregiving environment

Poor cognitive and academic outcomes are common consequences for children growing up in economically poor families. Poverty is associated with alterations in brain development, communication and cognitive skills. Children living in poverty are exposed to poverty-related risk factors and stressors, including less language exposure. Little is known about the early development of language and cognitive […]

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