Combining cortical stimulation and ‘mirrored’ visual feedback to enhance recovery of upper-limb: a pilot study.

Stroke is one of the most prevalent neurological conditions worldwide, especially among the elderly.

Motor impairment is one of the main disabilities associated with stroke. The ability of training and

physical activity to restore motor function after neural injury has long been appreciated. Nevertheless,

even with intensive task-specific training and physical activity, 15–30% of patients with stroke are

permanently disabled. As a result,research aiming to develop novel therapies that enhance

neuroplasticity is currently being conducted to allow rehabilitation of these patients. A promising

approach is modulation of cortical excitability using non-invasive brain stimulation techniques. These

techniques may instantaneously induce plastic changes within the cortical network of sensorimotor

areas, thereby improving motor function of the affected hand after stroke. Our work attempts to

elucidate whether repetitive administration of inhibitory non-invasive brain stimulation of the

unaffected hemisphere in sub-acute stroke over several days combined with sensorimotor

behavioural training using optical left-right reversing prisms could result in an enhanced effectiveness.

The primary objective is………….TBC

Faculty Supervisor:

Richard Staines

Student:

Partner:

Sunnybrook Health Sciences Centre

Discipline:

Life Sciences

Sector:

University:

University of Waterloo

Program:

Accelerate

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