Xenon has developed isoform selective blockers of the sodium channels that are expressed in CNS neurons with the intent of developing them for therapeutic use, especially epilepsy. The primary goal of this research project is to determine the activity of compounds on CNS neurons. Until now, all characterization has been done with heterologously expressed channels. […]

Infertility is a health issue that affects over half a million Canadian of childbearing age. Half of these cases are related to male reproductive dysfunctions. While semen analysis provides information about some causes of male infertility, about thirty percent of these cases remains unexplained. In this context, the main goal of our project is to […]

Poor diet is one of the factors associated with obesity and overweight, which may increase the risk for chronic diseases such as diabetes, heart disease and cancer. Two ways to improve the diets at the population level are to 1) establish public health initiatives (e.g. product labelling or advertising restrictions and 2) change the portion […]

Poor diet is one of the factors associated with obesity and overweight, which may increase the risk for chronic diseases such as diabetes, heart disease and cancer. Two ways to improve the diets at the population level are to 1) establish public health initiatives (e.g. product labelling or advertising restrictions and 2) change the portion […]

Poor diet is one of the factors associated with obesity and overweight, which may increase the risk for chronic diseases such as diabetes, heart disease and cancer. Two ways to improve the diets at the population level are to 1) establish public health initiatives (e.g. product labelling or advertising restrictions and 2) change the portion […]

Stroke is the third leading cause of death in Canada and France, and a major cause of disability world wide. Physiotherapy rehabilitation programs are used to improve movement through neural adaptations, also known as neural plasticity, in stroke patients. During this project stroke patients, will be performing individualized rehabilitation programs that include weekly clinical assessment […]

The objective of this research proposal is to develop a framework to track and manage the fatigue of pilots involved with aerial firefighting. Interns of different backgrounds (neuroscience, engineering and statistics) will work together to achieve this goal. The neuroscience intern will collect physiological data to identify how a pilot’s physical and cognitive performance is […]

Obesity and diabetes are leading nutrition-related disorders among pets in North America and have significant impacts on animal morbidity and mortality. The glycemic index, a measure of post-prandial blood glucose response, has been shown in humans to significantly impact glucose control, insulin sensitivity, weight management, and chronic disease risk. In pets, the effects of carbohydrates […]

Canada’s population is aging rapidly and faces several challenges with their physical and mental health. At the same time, portable technology and wireless Internet access stand to revolutionize how Canadians manage their own health and interact with the healthcare system. Here, we will identify ways in which Canadians can use technology to proactively manage and […]

It is well established that livestock producers are effective land stewards and contribute to high productivity and wildlife habitat on grazed lands. The effectiveness of many management practices are established, but uncertainty remains, particularly in interactions between practices at large-scales. We propose to track grazing patterns of bison and cattle using GPS collars at the […]

Emulsifiers, specifically diacylglycerides and monoacylglycerides, have the potential to replace fats and oils high in saturated fats such as palm and thus provide healthy and low-caloric food products. Canola based DAGs and MAGs not only can reduce the saturated fat content and food calories, they also can improve the functionalities of food products. However, they […]

The high incidence of acute organ rejection following heart transplantation poses major problems for patients, clinicians, and the healthcare system. A major clinical challenge in this regard arises from the difficulty of accurately and efficiently diagnosing when organ rejection occurs. In Canada, the current approach to diagnosing acute rejection requires taking small pieces of the […]