The high incidence of acute organ rejection following heart transplantation poses major problems for patients, clinicians, and the healthcare system. A major clinical challenge in this regard arises from the difficulty of accurately and efficiently diagnosing when organ rejection occurs. In Canada, the current approach to diagnosing acute rejection requires taking small pieces of the […]

Alewife (Alosa pseudoharengus) is a key species in the ecology of the upper Bay of Fundy, Canada, that provides food to numerous predators and scavengers. Each year, Alewife migrate into freshwater systems to spawn in lakes. Dams and fishways often impede the migration of Alewife, which can have detrimental effects on Alewife populations, as well […]

Les changements climatiques auront des effets importants sur la forêt canadienne. L’augmentation de la température combinée à des précipitations stables pendant la période de croissance, amèneront une diminution du contenu en eau des sols forestiers et augmenteront la probabilité de sécheresse intense dans le futur. Malgré quelques études récentes, les impacts sur les forêts au […]

Les sols contaminés sont une problématique environnementale importante au Canada. La phytoremédiation (l’utilisation de plantes afin de décontaminer les sols) est une approche efficace qui s’inscrit dans un contexte de développement durable. L’étape subséquente est l’intégration de la phytoremédiation dans un contexte plus vaste d’économie circulaire permettant le développement économique tout en étant socialement acceptable. […]

Nearly 70% of all drug candidates are not pursued for pharmaceutical development because they cannot be dissolved into solutions appropriate for human use. Cuprous Pharmaceuticals Inc. (CPI) recently discovered that some of these drugs could be dissolved in the presence of certain metal ions. Furthermore, a number of metal-drug complexes are more therapeutically active than […]

Metaplex is a new approach to prepare metal-based drugs (metal complexes) for use in humans. It has been patented by BC Cancer and is in the process of being licensed to Cuprous Pharmaceuticals (CPI), the company which I helped to create and I currently work for. Metal complexes (MCs) are a new class of drugs […]

Dans le cadre de ce projet, l’étudiant-e stagiaire évaluera l’impact d’un supplément quotidien de poudre d’algues brunes (InSea2) sur différents paramètres liés à la prévention du diabète chez une population à risque. L’étude évaluera également la contribution du traitement sur la perte de poids associée à un programme de perte de poids modérée. Le (la) […]

The “Fearless Physical Activity” workshops are designed to educate and introduce children with congenital heart disease (CHD) to physical activities that are safe for their health. These workshops will provide opportunities for children with CHD and their families to try new activities and to learn about the benefits of lifelong physical activity, specific to those […]

Treatments that involve activating a patient’s own immune system, immunotherapies, are becoming important cancer therapies. Unfortunately, doctors don’t always know the best way to combine these therapies to best treat patients and the current tools they have to evaluate treatment success don’t work well for immunotherapies. Molecular imaging, particularly magnetic resonance imaging (MRI) or positron […]

University of British Columbia and Amgen British Columbia (ABC) will collaborate to develop a safe and efficient lipid-based vaccine delivery system that can be used in laboratory animals to enhance the production of specific antibodies against difficult targets. These antibodies can be further screened and characterized for treating various diseases in humans.

Women with breast cancer often undergo mastectomy, or removal of the breast. Afterwards, they may elect to reconstruct their breast using one of several methods. One of these methods is by implantation with a permanently adjustable prosthesis. This procedure may show a smaller budgetary impact compared to multi-staged implantation. This project will estimate the budgetary […]

Pacific herring, as forage fish, provide a vital ecosystem service within marine food webs, as well as economic benefits to BC’s commercial herring industry and cultural benefits to coastal Aboriginal communities. Building on innovative participatory research in Haida Gwaii, this project will identify the values of BC herring industry stakeholders and their preferences for management. […]