Efficacy and insect resistance management of new insecticidal proteins targeting western bean cutworm in Ontario, Canada – Year two

Western bean cutworm (WBC) is the most important corn pest in Ontario and lack of control can reduce grain yield and quality due to insect feeding and mycotoxin contamination. Unlike other primary corn pests, WBC are not controlled by most transgenic corn expressing Bt proteins. Monsanto has developed new insecticidal proteins to which WBC are […]

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Next-generation sequencing for the analysis of antibody development in vaccinated rabbits (Oryctolagus cuniculus) and in a humanized rat (Rattus norvegicus OmniRat) model.

ImmunoPrecise antibodies is a company that specialized in the production of custom antibodies, the Y-shaped molecules produced by living things to defend itself from infection. Their ability to recognize and bind to specific targets allows for their use in diverse scientific analyses where their specificity of binding is manipulated to allow for localization and/or isolation […]

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Motion and Attenuation Correction for PET/MRI

During a medical imaging exam, patient motion such as breathing, cardiac motion, and random adjustments of the head or body can affect the accuracy of the acquired images. Positron emission tomography (PET) is a powerful medical imaging technology that can detect minute amounts of an injected probe targeting specific tissue processes and diseases. Magnetic resonance […]

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Development of a next-generation in vivo human gene-editing therapeutic platform

The over-arching goal of our project is to develop a robust next-generation gene-editing platform to repair the deleterious mutations that are responsible for genetic diseases such as Cystic Fibrosis and cancer. First-generation precision endonuclease technologies have been tremendous for in vitro gene disruption studies and ex vivo treatments, but there has been limited success at […]

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Development of a next-generation in vivo human gene-editing therapeutic platform – Year two

The over-arching goal of our project is to develop a robust next-generation gene-editing platform to repair the deleterious mutations that are responsible for genetic diseases such as Cystic Fibrosis and cancer. First-generation precision endonuclease technologies have been tremendous for in vitro gene disruption studies and ex vivo treatments, but there has been limited success at […]

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Towards creating intelligent heat stress monitoring and management solutions to safeguard health and wellness

The scientific challenge for this research project is to advance our understanding of the impacts of heat stress in heat vulnerable workers and to use this information towards the creation of intelligent heat stress monitoring and management solutions to safeguard health and wellness. Currently, our understanding of the effects of heat exposure on vulnerable individuals […]

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Needs assessment of challenging behaviours in children with Fetal Alcohol Spectrum Disorders (FASD) and coping strategies from the stakeholders’ perspective

The objectives of this project are to determine the behavioural and emotional problems affecting children with FASD and their parents/guardians and to determine the specific services and supports this group requires to deal with the identified challenges. This information will be gathered by telephone interviews of 100 parents/guardians and 30 clinicians. The intern will be […]

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Formulating a novel goat-whey based drink and studying its nutritional and health functions – Year two

This project will create novel goat milk-based products and test their health effects in healthy adults. Interest in goat milk is increasing, mainly due to two market trends: consumers’ new taste trends for niche/ethnic products, and the perception of goat milk having added health properties. Goat milk is perceived as having intestinal anti-inflammatory effects and […]

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Behavioural Economic Interventions to Promote Health and Wellness on a Canadian Mobile Health Application

Behavioural economics demonstrates that people consistently behave in irrational ways that lead to poorer health outcomes. Yet the way in which people behave irrationally is predictable, which governments and organizations around the world have used to design “nudges” to “[alter] people’s behaviour in a predictable way without forbidding any options” (Thaler & Sunstein, 2008). Carrot […]

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