The purpose of this research will be to analyze microbial volatile organic compounds for the purpose of the development of an analytical method for the detection and speciation of moulds in an indoor environment.

Chronic inflammation is the common denominator for various diseases, including atherosclerosis, age-related macular degeneration (AMD), obesity, type-2 diabetes, liver diseases and even cancers. In most cases, this inflammation is the result of massive pro-inflammatory macrophage infiltration in tissues, due to their aberrant signalling and dysfunction, in presence of fat accumulation. The CD36 scavenger receptor has […]

The mining sector plays a huge role in the Saskatchewan economy, in addition to being the largest private sector employer of Aboriginal peoples in the province. It is important economically and socially for the mining workforce to be healthy and productive. Yet we know little about the impacts of physical and mental health on productivity, […]

Acute Lymphocytic Leukemia (ALL) is a common form of leukemia that affects approximately 3 people per 100,000 individuals, and is the most common form of cancer in children and adolescents. Current therapies are effective in children, however, treatment success in infants, adolescents, and adults needs improvement. Indeed, there is a need for new chemotherapeutic drugs […]

Pulmonary arterial Hypertension (PAH) is a severe disease that affects both the pulmonary vasculature and the heart with no curative options. The apelinergic system which can be defined by the cell surface receptor APJ, mostly expressed in the heart and vessels, and its endogenous ligands Apelin and ELABELA appear as a promising therapeutic pathway in […]

A higher incidence of colon cancer is reported in populations consuming high amounts of red meat, as well as in patients with inflammatory bowel disease, where gut bacteria participate in the development of inflammation. We found that dietary supplementation with heme, an element found at high levels in blood, is detrimental to gut health and […]

Les tourbières représentent la majorité des milieux humides du Québec et offrent une diversité floristique unique. Cependant, les gradients structurant leur biodiversité restent mal connus. Cette compréhension est toutefois essentielle afin d’orienter adéquatement les choix de conservation. Nos objectifs sont 1) de modéliser la répartition de la diversité floristique des tourbières; 2) d’étudier la dynamique […]

G protein-coupled receptors (GPCRs) are proteins present on the surface of a cell that are the targets of >30% prescription drugs. These GPCRs are involved in various diseases ranging from hypertension, airway diseases to taste disorders. Detection of antibodies for GPCRs in various disease states is a challenging task. The main goal of this project […]

There is emerging evidence from studies at the Montreal General Hospital supporting the effect of prehabilitation (also referred to as preoperative conditioning) on postoperative outcomes. Increasing physical fitness and optimizing nutrition in cancer patients before surgery can help patients feel physically stronger, return to their community functions sooner and potentially undergo adjuvant cancer treatment earlier […]

Les chutes chez les aînés sont un problème de santé publique sérieux. Actuellement, les services mis en place pour prévenir l’augmentation du nombre de chutes au sein de la population québécoise s’inscrivent majoritairement en prévention secondaire et tertiaire, pour une clientèle âgée de 65 ans et plus à risque de chute, ou ayant déjà chuté. […]

Evaluating the impact of multiple stressors on aquatic ecosystems often requires robust biodiversity estimates. Traditional methods for sampling fish communities are very costly, may have a significant share of inaccuracy and require specialized taxonomic expertise and have numerous other inherent limitations. The general objective of our proposed project is: • to develop and validate genomic […]

Type 2 Diabetes (T2D) is a major cause of death worldwide (“WHO | The top 10 causes of death,” 2014). In Mexico, high incidence rates of diagnosed T2D (9.2%) and obesity (34.4%) pose a burden for the health system (Instituto Nacional de Salud Publica (INSP), 2012b). A national strategy for diabetes management, the Grupos de […]