Type 2 diabetes (T2D) results in high blood sugars and can cause serious complications. Recent studies suggest that treatment with diabetes medications along with lifestyle changes can result in patients not needing diabetes medications for months or even years, a concept known as diabetes remission. The Remission Evaluation of Metabolic Interventions in Type 2 Diabetes […]

An increasing number of consumers favor minimally processed products from natural ingredients for reducing the intake of chemical additives from food products. One of the major problem for the food industry is the lack of natural additives. The main objective for this research is to develop and optimize natural, safe, effective and affordable antimicrobial additives […]

Blood cancer (leukemia) is common, with ~48,600 and 6,400 new cases expected in the United States and Canada respectively in 2016. The National Cancer Institute (US) calculated an overall 5-year survival rate of 56% for various blood cancers. This is because most current therapies are short-lived; drug resistance and relapse pose significant clinical problems. Life-long […]

This research will investigate use of calcium oxide treated straw (CaOS) to increase fibre levels in wheat-based feedlot cattle finishing diets. In vitro total gas production will be measured to determine the ideal treatment protocol for creation of CaOS. Further in vitro work will compare fibre digestibility of CaOS to untreated straw, barley silage and […]

Seizures are rare while dreaming in rapid eye movement (REM) sleep. New research, however, suggests seizures may rebound during unstable REM sleep. This may be due to brain wiring (“connectivity”) since a highly connected brain is more prone to seizures, and connectivity changes from wakefulness to sleep. Brainwave tracings (“EEG”) can generate connectivity maps (“connectomes”) […]

Noblegen Inc. is an advanced bioproducts manufacturer dedicated to developing cost-effective, naturally-derived biomaterials and biochemicals for a wide range of consumer and industry sectors. We employ a unique organism, algae, to continue to do what it does naturally – decontaminate wastewater sustainably and affordably while also generating valuable biomass for use in biomaterials and biochemicals […]

When plants are stressed they produce “reactive oxygen species” (ROS). Plants manage ROS with specific enzymes, many of which require micronutrients for activity. In the case of herbicide tolerant crops, the application of herbicide kills weeds in the crop but also stresses the crop for a time. The proposed work will test the hypothesis that […]

Evaluation is a key element to assure the high quality of programs. The Pre-Residency program is meant to prepare the international medical graduates to be at the same level as any locally trained Medical graduate in Canada for their specialty training rotations. In this project we are using an innovative engineering approach to conduct an […]

As a primary cancer progresses to the deadliest form, metastatic cancer, the cells undergo several genetic and epigenetic alterations referred to as the metastatic gene signature. Part of a metastatic gene signature is the downregulation of genes associated with immune recognition, which can be seen in multiple cancer types as the down regulation of the […]

Fear is considered a natural reaction when a child visits the hospital. Much research has been done to understand what causes it and how to treat it. Current methods to treat child hospital fear works on decreasing anxiety at specific points in the procedure. This project will investigate creating a series of tools and procedures […]

This project aims to assess a number of novel exercise training techniques to improve exercise performance in elite Canadian Wheelchair Rugby athletes. The first training technique to be assessed is training in the heat, a condition that many Wheelchair Rugby players may have difficulty competing in, to lead to adaptations that will improve performance in […]

This research project aims to develop a novel treatment for diabetic foot ulcers. Individuals with diabetes (3.4 million Canadians) exhibit impaired healing of acute wounds, and 15% (~510,000) are estimated to develop chronic non-healing diabetic foot ulcers (DFUs). DFUs precede 84% of all diabetes related lower leg amputations. Typical DFU treatment is excising devitalised tissue […]