Improving implementation of the intensive lifestyle intervention and accuracy of lifestyle data collection in the REMIT-Dapa trial.

Type 2 diabetes (T2D) results in high blood sugars and can cause serious complications. Recent studies suggest that treatment with diabetes medications along with lifestyle changes can result in patients not needing diabetes medications for months or even years, a concept known as diabetes remission. The Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT) pilot trial was done to look at the effect of lifestyle changes and diabetes medications in people with T2D. A large REMIT trial was recently started to look at the effect of a similar intervention in causing diabetes remission. The lifestyle changes involve >5% weight loss and 150 minutes of physical activity per week. It would be worthwhile to assess techniques used by the research nurse, dietitian and kinesiologist that contributed to people accomplishing their lifestyle goals. It is also worthwhile to look at people who accomplished their lifestyle goals and see what helped them be successful. The aim of this analysis is to provide this information to centres facing difficulties achieving the lifestyle component. Also, there is an opportunity to improve the way physical activity and diet information is collected during the current trial.

Faculty Supervisor:

Natalia McInnes

Student:

Farah Sultan

Partner:

AstraZeneca

Discipline:

Medicine

Sector:

Medical devices

University:

McMaster University