There is much about the brain we still do not understand. But, one fundamental way to understand how the brain works is to know normal range of activity. For example, how does your physician know that you have normal blood pressure? Similarly, why did the medical community choose “120 over 80”? The way we do […]

Immunovaccine Inc. is developing immune therapies for cancer using the company’s DepoVaxTM vaccine technology. DepoVax is a patented formulation provides controlled and prolonged exposure of antigens and adjuvants to the immune system, resulting in a strong, specific and sustained immune response. Immunovaccine’s translational research team is focused on improving responses in advanced cancers by combining […]

Using growth media available from Stemcell technologies, along with our own tools and techniques, we can isolate and grow intestinal stem cells from mice or human patient donors into enteroid cultures. Enteroids are 3D cell cultures that replicate many of the structures and types of cells found in the intestinal lining. We propose to work […]

Humpback whales show remarkable recovery after the impacts of commercial whaling, and their consumption of essential food resources could affect local herring and salmon populations. Little is known about the feeding ecology of humpback whales in BC waters, despite their increasing importance to fisheries and tourism. Both humpback whales and fish are vulnerable to prey […]

Healthy and productive coastal regions are highly important to Canada, both socio-economically and for the ecosystem services they provide. In 2015, the Vancouver Aquarium launched a new coast-wide initiative in British Columbia (PollutionTracker) to assess coastal health by generating high quality contaminant data for mussels and nearshore sediments. In the proposed study, Dr. Gabriela Aguirre-Martinez […]

The goal of this project is to provide evidence of validity for two newly developed measures of quality of life; one for hidradenitis suppurativa (HS) and one for acne. Both HS and acne negatively impact quality of life; however, to date, there are no disease-specific, patient-centered quality of life measures. The results of this project […]

Fibroproliferative disorders are the leading cause of morbidity and mortality worldwide. A large group of interstitial lung diseases (ILD) can cause progressive scarring of lung tissues, affecting the ability to breathe. Idiopathic Pulmonary Fibrosis (IPF) is one of the major forms of ILD and is characterized by a progressive decline in lung function. Although the […]

Wize Monkey is currently the only maker of Coffee Leaf Tea in the world; they work in partnership with coffee producers in Nicaragua to develop alternative coffee based products. One of these is coffee leaf; a novel idea of harvesting leafs at optimal times to be used as a tea-based beverage. The leaf is harvested, […]

Walking pattern in healthy adults changes with age. A poor walking pattern results in fall and fear of falls. It is important to detect early changes in gait so that corrective measures are taken. In this project I am planning to use a sensor (Heel2Toe device) that detects when an individual makes a correct step […]

Manufacturing of consistently high quality products is the commitment of the pharmaceutical industry. To achieve this, new products must be thoroughly tested and the results must meet government-approved product specifications. Improving existing and adopting improved analytical technologies for product testing ensure the production of safe and effective products. This is particularly critical for the manufacturing […]

This project will determine if abnormal behavior of the visual system correlates with symptoms in patients with concussions. Our first step will be to ensure that we obtain the same values for each of 7 tests when we measure a healthy person twice within a short period of time (called reliability). Next, we will see […]

Le but du projet de recherche est de développer une thérapie pour une maladie héréditaire sévère appelée l’Ataxie de Friedreich. Cette maladie est due à une mutation dans le gène de la frataxine qui réduit la production de cette protéine mitochondriale. Des expériences seront faites sur des souris modèles de cette maladie. Comme les patients, […]