Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease lung disease with unknown cause. There are limited treatment options for IPF and investigations into new treatment options is needed. BOLD-100 is a clinical-stage small molecule that is currently being investigated as a treatment option in oncology and viral infections. The pathway that BOLD-100 impacts, […]

Given the public health-care system in Canada, many drugs are paid through by the provincial drug plans. Our government makes decisions on which drug to pay for through a process known as health technology assessment whereby manufacturers submit a document that details the clinical, economic and other aspects (e.g. ethical, social) relating to their drug. […]

There are three legal clinics funded by Legal Aid Ontario that addressed the needs of workers. There is a need to better understand the work of the legal clinics and the needs of the populations they serve in order to guide their ongoing work. The objective of this project is to co-design a framework of […]

This research project is related to the development of innovative solutions to enhance thermal performance of self-contained DM systems. The project will be carried out in collaboration with Van der Graaf Inc. (VDG), which is a Canadian company located in Brampton, Ontario. A long-term plan has been developed by the applicant and the industrial partner. […]

Video endoscopy is the main diagnostic and screening method for cancer screening in the gastrointestinal (GI) tract. Currently, the endoscopic video is not sufficiently documented, which makes reviewing of these videos difficult. The research team will partner with the company to develop an audio/video recording technology to combine physician voice annotation of the video during […]

The Niagara Escarpment is a dominant landform in southern Ontario and provides the region with exceptional sites of natural beauty including numerous waterfalls and exposed rocky cliffs. However, the escarpment is also a geomorphic feature formed by ongoing erosion processes that create many challenges for those living near or enjoying its natural beauty. Unfortunately, there […]

MicroLED displays are of growing interest and are seen as a next generation display technology for leading-edge displays of all sizes, from head-mounted displays for virtual reality through portables (watches and cell phones) to televisions and wall-size displays. Red, green and blue light emission from blue-emitting Light Emitting Diodes (LEDs) would replace the use of […]

Severe and multiple traumas can lead to post-traumatic stress disorder (PTSD) which causes distress and difficulty in many areas of life. Military members, veterans, and public safety personnel such as police officers, firefighters, and rescue workers are often exposed to traumatic events on-the-job (seeing natural disasters, human violence, or death). One severe subtype of PTSD […]

The main goal of this project is to develop a platform that helps to optimal design of a power converter for switch reluctance motors. The research will focus on multi-domain models and multi-objective optimization routines. Due to the high complexity of developing such a tool, the component models will include loss, thermal, and cost aspects, […]

As part of reforms to the regulations governing Canadian banks, new rules governing the capital to be set aside for market risk have been proposed, termed the Fundamental Review of the Trading Book (FRTB). With the new rules, some Canadian banks will move to calculating capital requirements using a regulatory Standardized Approach. The goal of […]

Climate change is one of the greatest challenge society has ever faced, with increasingly severe consequences for humanity. Climate change also creates risks to both the safety and soundness of the individual firms and to the stability of the financial system. This will be felt both in the cost of direct losses to climate events, […]

The purpose of the project is to compare how well the neuro-compensator (NC) hearing aid restores various aspects of auditory perception relative to a standard technology used in the industry, called wide-dynamic range compression (WDRC). Specifically, the intern will test individuals on their ability to comprehend speech, to make fine discriminations of musical sounds, and […]