Cellular imaging enables the study of diseases in myriad ways, consequently impacting human health. Through visualizing individual cells, clinicians are able to diagnose diseases and scientists are able to develop drugs to treat them. There are many powerful tools to visualize cells, including fluorescence and electron microscopy. However current common imaging techniques fall short for […]

MRCK is an enzyme that has shown promise as a target for the development of new drugs to treat several aggressive cancers, including glioblastoma (GBM) and high grade serous ovarian cancer (HGSOC). BDP9066 is a highly potent and selective inhibitor of MRCK reported first in 2018. Despite excellent activity profile, BDP9066 is not a realistic […]

This project revolves around advancing the field of structural dynamics, with a specific focus on the structural analysis of plates, particularly those made of Functionally Graded Materials (FGMs). The work will use three approaches for structural analysis: • The first one emphasizes developing novel and highly convergent analytical and semi-analytical methods that address the complexities […]

Currently, energy audits at Dillon Consulting Limited take 2 to 3 days to generate comprehensive reports, consuming significant auditor time due to the manual process. This inefficiency diverts auditors from critical tasks and introduces inconsistencies, especially in buildings with multiple facilities. It limits Dillon Consulting’s ability to meet increasing demand for energy management practices. There […]

Working with Sunnybrook hospital’s Green Task Force, we will be collecting information on their reduction of material and textile waste, innovative technologies as to the process of change, and then creating an interactive art piece in the central lobby to showcase the advancements and celebrations that these new processes have helped the hospital, the diversion […]

The proposed scientific collaboration is toward developing a new class of porous structure using mathematical design. The structure must be lightweight and capable of removing heat. This structure is advantageous in engineering, such as heat enhancement, heat exchangers, and biomedical engineering (hip, jaw, or femur replacement). The global importance of the proposed research is in […]

Design an efficient way to store and organize the large amounts of data required by our real time bidding application. Data such as campaign information, campaign assets (images, links, html) campaign targeting settings, and campaign optimization data could be arranged for fast access and processing inside the RTB application. Efficient storage and processing methods are […]

Infertility affects 15% of couples in the U.S. and Canada, with 20-50% of cases linked to male factors. Current treatments like Intra-Uterine Insemination (IUI) are costly, invasive, and have low success rates (5-15% per round), creating significant barriers for couples. Fertilead Inc. addresses these challenges with FertilEZ, a self-administered at-home fertility kit that improves sperm […]

This research project focuses on improving how we detect fraudulent activities, such as suspicious transactions, in large financial transaction networks like Mastercard’s. Fraudulent transactions are rare and difficult to catch because they often look similar to regular transactions, and there are limited accurate data to rely on. To tackle this, we are using Graph Neural […]

Parkinson’s disease (PD) is a challenge for many as the world’s population ages. Pain is a common problem for people with PD, and usual pain treatments often have side effects. Some PD patients find relief in singing, which also helps with voice difficulties related to PD. There’s evidence suggesting that group singing might even reduce […]

This project will develop an innovative touring strategy for Why Not Theatre’s production of The Mahabharata, expanding its reach across domestic and international markets. The intern will collaborate with theatre professionals to design a business model that enhances touring efficiency, audience engagement, and financial sustainability.

With the pressing need to reduce energy from carbon emitting sources, electrification of buildings is a crucial step forward. Electrification requires identifying activities and equipment that use energy received from carbon emitting sources and transitioning them to electric alternatives. The proposed research focuses on developing methods and strategies to overcome challenges associated with building electrification […]