Vaccination remains the most effective preventative measure for influenza infection. Seasonal influenza epidemics and the emergence of pandemic strains have increased the global demand for influenza vaccines, putting significant pressure on vaccine manufacturers. However, current vaccine manufacturing strategies rely primarily upon production in eggs, an age-old method that needs to be significantly improved. Recently, research […]

Smoking and all other forms of tobacco exposure are known to cause extremely detrimental health effects. It is the leading cause of preventable morbidity and mortality worldwide, and quitting smoking can increase life expectancy by as much 10 years. Tobacco is associated with poor reproductive health outcomes, cardiovascular disease, lung cancer, diabetes, blindness, and much […]

The Internet of Things (IoT) connects a plethora of smart devices globally across various applications like smart cities, autonomous vehicles, and health monitoring. IoT systems are predominantly software-defined, making them susceptible to quality issues on a large scale. This research aims to improve IoT trustworthiness through simulation-based testing and automated fault localization. Existing IoT systems […]

The proposed research project aims to explore a cost-effective and eco-friendly method for recycling lithium-ion batteries (LIBs) used in electric devices and electric vehicles. Lithium, cobalt, nickel, and copper, which are considered critical metals, are present in LIBs, and they are essential to the operation of electric vehicles and devices. After their lifetime, these batteries […]

One crucial measure of heart function is how well it can pump blood from its ventricles, referred to as the ejection fraction (EF). One method of estimating the EF in Cardiac PET is to segment the myocardium of a ventricle on static gated images and compute the difference of the inner volume of the segmentation […]

This proposal explores the use of optimal transport in statistics and machine learning as well as develop one simple application in chemistry. Optimal transport is a well established mathematical field whose actors have gone to receive the most prestigious recognitions. Its inventor, Leonid Kantorovich, received the Nobel Prize in Economics. Cedric Villani, who wrote the […]

Le retrait est un phénomène de contraction volumétrique des matériaux cimentaires lors de leur prise et durcissement. Il est dû à l’évaporation de l’eau du béton. Ce phénomène n’est pas sans impact sur la fonctionnalité et la durabilité des ouvrages. Car il se caractérise le plus souvent par des fissures qui nuisent aux aspects esthétiques […]

The research will help the partner organization expand their in-house capacity for new product development and commercialization. Focused on wellness and sustainability, the partner aims to leverage green technologies to develop their patient-preferred variety of cannabis, which is current available as dried flower, as a cannabis oil. The partner also seeks to address the underutilization […]

Cardiac arrhythmia represent a major health issue in Canada, as well as in Europe, as they may lead to sudden death. Accurate means of detection need patients to undergo invasive and perilous exploration, because understanding of electrocardiograms is currently limited. To improve non-invasive detection, it is in particular interesting to understand the physical and mathematical […]

Chronic stress increases the risk of developing neurodegenerative diseases like Alzheimer’s. Specifically, chronic stress can cause increased microglial activation, leading to the release of pro-inflammatory cytokines through the NLRP3 inflammasome pathway. Pro-inflammatory cytokines play a role in the development and progression of certain brain diseases. Cerebiome has been associated with a reduction of pro-inflammatory cytokines. […]

Le sang appartient à une famille des suspensions particulièrement complexe : il s’agit d’une suspension dense de globule rouges très déformables et interagissant entre eux, ils peuvent par exemple s’agréger. Bien qu’étudié depuis les années 70 par les physiologistes, les mécanismes de ses écoulements complexes ne sont toujours pas bien compris. Le but de ce […]

Fatty liver disease, the most common complication of type 2 diabetes (T2D), affects 1 in 5 Canadians. If not managed or treated, a proportion of patients with fatty liver disease may develop the irreversible phases of liver failure, and hepatocellular carcinoma. A new class of drugs, SGLT2 inhibitors (SGLT2i), has been approved by Health Canada […]