Optimization and compatibility study of a pH-responsive terpolymercomposite membrane for controlled release dosage forms

A new film coating that can respond appropriately to different pH conditions of the stomach and small intestine (GI tract) was successfully prepared by combining pH-responsive nanoparticles with ethylcellulose polymer. However, the performance of the composite membrane has not been optimized for controlling drug release in the GI tract. Therefore, improvements are to be made […]

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Annual survey of Ontario’s publicly funded education system

Over the past 15 years, People for Education has conducted a survey of Ontario’s publicly funded schools. From this large-scale survey, People for Education produces research reports on public education in Ontario that are widely disseminated to the public and have been instrumental to informing educational policy in the province. The core objectives of this […]

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Voice Transformation for Interactive Digital Media

The main purpose of the research project is to have the student investigate and develop a voice transformation system that modifies waveforms of recorded speech segments to produce multiple different sounding voices for characters within a video game.

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Development of dual antibody therapies for cancer

Cancer is a devastating disease defined by genetic changes that result in the activation of proteins that encourage cell growth or prevent cell death. Modern oncology aims to specifically target these tumour-promoting proteins, which has the secondary benefit of leaving normal cells unharmed, unlike chemotherapy. Recently, a number of drugs that specifically block tumour-promoting proteins […]

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Development & Pilot Evaluation of an Online Peer Support Program for Family Caregivers of Ventilator-Assisted Individuals Living in the Community

Ventilator assisted individuals (VAIs) living at home are frail and generally cannot perform most daily activities. This is similarly the case for the palliative population of those with amyotrophic lateral sclerosis (ALS). Although these individuals prefer to live and die at home, the family members who care for them often experience stress and poor health. […]

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Development & Pilot Evaluation of an Online Peer Support Program for Family Caregivers of Ventilator-Assisted Individuals Living in the Community – Year two

Although ventilator-assisted individuals (VAIs) prefer to live and die at home, the family members who care for them often experience stress and poor health. Peer support can mitigate health declines by decreasing caregivers’ isolation and increasing their sense of control. However, no peer support programs exist for this caregiving population. Online support can especially overcome […]

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Chemical and Microbial Contaminants of Medical Air in Healthcare Institutions

Administration of supplemental oxygen through medical air is a life-supporting measure essential for the management of severe primary respiratory conditions as well as secondary lung injury due to systemic insults such as trauma and sepsis. This medical air is often produced on site through devices which draw, compress and filter outside air in order to […]

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Preclinical evaluation of novel meningococcal vaccines

Neisseria meningitidis (Nme) is a bacterial pathogen that often colonizes the upper respiratory tract of humans without symptoms, but which may also develop into rapidly-progressing sepsis and meningitis that can be fatal. Nme has evolved elegant means to specifically interact with human cells and proteins in order to colonize, survive and the evade host immune […]

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Development and Evaluation of a Life Threatening Infections Point-of-Care Triage Test for the Fionet System

Febrile syndromes are among the most common causes of global illness accounting for approximately two billion episodes annually. However, most infections are self-limited and only rarely do they progress to critical illness. Our current inability to rapidly identify the small proportion of individuals who will progress to life-threatening infections (LTIs) is a major barrier to […]

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My Wellness Journey: A Health Promotion Study for Children and Youth with Disabilities

The purpose of this project is to support the development of wellness-focused interventions, including weight management, mental health and social well-being for children with intellectual and developmental disabilities (IDD). To date, the focus of health promotion interventions have primarily focused on typically developing children and adolescents, rather than those with IDD. The partner organization, Special […]

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