Recent discoveries show that neutrophils mainly die by formation of neutrophil extracellular traps (NETs) in Cystic Fibrosis airways. Therefore determining mechanism and identifying FDA-approved drugs that inhibit NETosis could provide novel options to treat CF lung disease. We aimed to do the comparative gene expression analysis during NETosis induced by different NET inducing agents (PMA,LPS,A23187) […]

Recent discoveries show that neutrophils mainly die by formation of neutrophil extracellular traps (NETs) in Cystic Fibrosis airways. Therefore determining mechanism and identifying FDA-approved drugs that inhibit NETosis could provide novel options to treat CF lung disease. We aimed to do the comparative gene expression analysis during NETosis induced by different NET inducing agents (PMA,LPS,A23187) […]

The structural performance of skyscrapers subjected to natural hazards such as strong winds and earthquakes has significant effects on the resilience of a city because of the recent boom in the construction of skyscrapers around the world. However, resilience is currently not explicitly considered in the design of tall buildings. Studies show that modern tall […]

The structural performance of skyscrapers subjected to natural hazards such as strong winds and earthquakes has significant effects on the resilience of a city because of the recent boom in the construction of skyscrapers around the world. However, resilience is currently not explicitly considered in the design of tall buildings. Studies show that modern tall […]

In human viral diseases, misbehaviour of the cellular machinery utilizing ubiquitin is frequently observed. Ubiquitin is a small protein that attaches to target proteins in human cells and signals for their destruction. Human deubiquitinases are enzymes that remove ubiquitin to keep protein levels in balance. Viral pathogens have evolved proteins that mimic human deubiquitinases to […]

In human viral diseases, misbehaviour of the cellular machinery utilizing ubiquitin is frequently observed. Ubiquitin is a small protein that attaches to target proteins in human cells and signals for their destruction. Human deubiquitinases are enzymes that remove ubiquitin to keep protein levels in balance. Viral pathogens have evolved proteins that mimic human deubiquitinases to […]

Antibodies are the fastest growing segment of the pharmaceutical market, and with modern engineering technologies antibodies can be programmed to target devastating diseases. Within the immune system, antibodies fight invading bacteria and viruses. High-quality synthetic antibodies directed to disease-related targets have immense therapeutic potential. Development of cell-based assays to enable rapid identification of functionally active […]

Most studies on violence employed by criminal groups are based upon the idea that illegal business, much like legal companies, benefit from the stability, certainty, and freedom that can be found in peaceful locations. Because violence generates mistrust, makes trade more costly, and draws the attention of the police, it is usually assumed that criminals […]

This project aims to help make neighbourhoods safer, healthier, and more economically vibrant by encouraging people of all ages to walk, cycle, and roll. Fewer children than ever before are walking and biking to school due to parents’ fears that local roads are unsafe. Unsafe roads and unwelcome pedestrian environments also negatively effect local businesses. […]

The continuously increasing demand for wireless access, driven by the increasing requirements of our connected society, is pushing current wireless cellular communication systems to the limits of their capacity. The objective of this project is to continue the successful collaboration with our industry partner (Telus Corporation) to further contribute to the evolution of current generation […]

The continuously increasing demand for wireless access, driven by the increasing requirements of our connected society, is pushing current wireless cellular communication systems to the limits of their capacity. The objective of this project is to continue the successful collaboration with our industry partner (Telus Corporation) to further contribute to the evolution of current generation […]

High-performance computing and communication infrastructure has reached an industrial scale, with equipment racks 100 meters long interconnected by cables carrying data at speeds exceeding 10Gb/s. This has led to growing interest in optical fiber communication for interconnect within infrastructure computing and communication installations, displacing conventional copper interconnect. Transitioning these relatively short-reach parallel links to optical […]