Small molecule agonists of SHIP1 for treatment of inflammatory disease

Activation of the immune system is necessary for defense against pathogens and injury, but just as important are the processes to turn this inflammatory response once the infection or injury has been resolved. Inappropriate prolongation of immune cell activation results in inflammatory diseases such as inflammatory bowel disease, asthma and arthritis. The University of British […]

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Integrated Optimal CLT Building Design Considering Energy Performance and Structural Performance

This research proposed a method to conduct optimal CLT building design, which has minimum CLT usage and minimum operating energy consumption. This is a multidisciplinary research pushing the boundary of current definition of optimal design for each disciplinary to another level. With the developing of Building information modeling and automized simulation-optimization technology, the design of […]

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Towards an Elastic and Reliable Cloud Resource Management

This work is a holistic automatic methodology for cloud resource management system, which is a corner stone to build any cloud system. Cloud players rely on this to reduce management effort and cloud running cost, by enabling dynamic service access to cloud clients with cheapest price for customer, and high revenue for cloud providers. Customer […]

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Building Standards for Online Voting: Safeguarding the Industry

This goal of this project is to develop a Standards Proposal and initial framework to guide the use of online voting in municipal elections in Ontario. Elections in municipalities in Ontario are among the most digital in the world, yet there are no guidelines to shepherd use of the technology. Working with our partners we […]

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Responsive polymer-based sensing system for COVID-19 infection

Monitoring hormone levels in saliva can be used to assess female reproductive health, which can yield many benefits to individuals. For example, those that have fertility issues can use hormone levels in saliva to improve their chances of conception, while the monitoring hormone levels over time could also be used to track and help treat […]

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Pilot Plant for Lithium Extraction from Saskatchewan Brine Deposits

With the growth in demand for electric vehicles and mobile devices powered by rechargeable lithium batteries, demand for lithium is expected to increase by over 200% in the next decade. Current lithium production comes primarily from Australia, South America and China. There are significant lithium reserves in the same Saskatchewan aquifers currently being exploited for […]

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Topologies and Linearization of High Peak-to-Average Power Amplifiers for Digital Broadcast Radio Applications

Broadcast radio is changing from an analog medium based on frequency modulation (FM) to a full digital broadcast based on orthogonal frequency division multiplexing (OFDM). The high peak-to-average power ratio of the OFDM waveform requires different power amplifier topologies and a high degree of linearity. The research in this project analyzes current amplifier performance for […]

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AI powered mobile application to detect plagiocephaly and craniosynostosis in infants

Technology can be a valuable tool to help physicians improve the care they provide for their patients. We set out to determine if an AI powered mobile application could help primary care physicians detect clinically significant positional plagiocephaly and/or craniosynostosis during regular well-baby visits. The intern will directly help in planning, conduction, and statistically analyze […]

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Enhanced carbon capture in manipulated mine tailings

This project will study the effects of CO2 sequestration in mine waste tailings using a robotic mixing system. Mine waste tailings represent a large opportunity for carbon storage, assisting mining companies with goals to improve their carbon footprint. Robotic mixing of the surface of tailings is expected to accelerate carbon storage and mixing and measurement […]

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Engineered genetic traceability solution for commercerical ale yeasts and methodology for rapid dectection and identification of diastatic yeast contamination in beer fermentation

This project will demonstrate that one or more unique DNA ID sequences (“DUID”) can be inserted into the genomes of select strains of Saccharomyces cerevisiae ale yeast and S. cerevisiae var diastaticus yeast strains without affecting the heritable traits of the host and then the DUID can be recalled upstream in the brewing process. By […]

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Computer-Aided Detection of Non-Alcoholic Fatty Liver Disease (NAFLD), Steatosis and NASH, using Raw Signals from Point-of-Care Ultrasound and Deep Learning

Fatty Liver Disease affects approximately 20% of the Canadian population [1]. Furthermore, 4% of Canadians have developed serious inflammation and damage as a result of fat build-up in the liver [2]. This can quickly progress causing liver scarring and cancer [2]. Fatty liver disease requires early diagnosis for effective treatment to be implemented but unfortunately, […]

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Development of a UV-LED based surface disinfection system

Respiratory droplets of pathogens, such as SARS-CoV-2 in the current COVID-19 pandemic, spread not only from person to person via direct contact, but also indirectly via contaminated frequently touched surfaces. Ultraviolet (UV) radiation is known as the gold standard of disinfection technology, where the DNA of microorganism are damaged by high energy UV photons. The […]

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