Standardization and optimization of saliva sample processing for SARS-CoV-2 detection without nucleic acid purification

The SARS-CoV-2 outbreak, which started in Dec. 2019, has so far not been contained due to unpreparedness and unsuccessful development of antiviral drugs against SARS-CoV-2. In response to this pandemic, we propose development of a diagnostic assay based on saliva samples. We will also standardize virus collection procedure and inactivation steps to reduce the turnaround […]

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Simulating dynamics of flux qubits with charge and hybrid flux noise

D-Wave Systems has designed processors based on a scalable architecture that aim to implement quantum annealing, an algorithm that can be used to solve a wide variety of optimization problems. A minimal requirement for a device to perform quantum annealing is that it maintains coherence throughout an appreciable fraction of the annealing protocol. In reality, […]

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Computational Fluid Dynamics Optimization of Very High Lift Coe?cient Airfoil

The proposed research project’s objective is to perform analysis on airfoil dimensions and configurations for a crosswind power kite system for wind energy generation. The airfoil will be examined through computational methods to determine how well the airfoil will perform. The airfoil configurations will then be optimized to find better designs for airborne wind energy […]

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Anomaly detection using AI/ML for Network Correction

Anomaly detection or outlier detection is a technique to identify rare items, observations or events which are differing significantly from most of the data or do not conform to the expected behavior of the system. Typically, anomalous data cause numerous problems in the computer networking and communication system. This project aims to develop an advanced […]

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Development, implementation and validation of new anti-E6 therapeutics for the treatment of HPV-associated cancer – Year two

Human papillomaviruses (HPVs) are responsible for almost all cervical cancers. Current treatment available relies on chemo- or radiation-therapy or surgery. These methods have several side-effects with high morbidity and survival of just ~ 70%. Our lab, therefore, develops a more patient-centered approach based on targeting the viral E6 protein, the main culprit of carcinogenesis in […]

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Process Development of Atomic Layer Deposition Cobalt and Ruthenium Metal Films – Year two

Next-generation integrated circuits require the innovation of new interconnect materials in order to maintain the performance improvements of Moore’s Law scaling. Cobalt (Co) and ruthenium (Ru) are two specific metals that are garnering strong interest for use in the filling of interconnects because of their better electrical performance and reliability at the extremely scaled dimensions […]

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Prioritization and Optimization of the Sewer Flushing Program for Municipal Wastewater Collection Systems

The objective of the study is to develop an algorithm to streamline and automate the decision making process for implementing the municipal wastewater collection flushing program. Traditionally, a municipal flushing program, or pipe cleaning, is based on a time-cycle approach. This means that all sewer pipes in the network are treated the same, ignoring variables, […]

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Modelling and Assessment of Cloud Based Smart Dual Fuel Switching System (SDFSS) of Residential Hybrid HVAC System for Simultaneous Reduction of Energy Cost and Greenhouse Gas Emission Under Smart Grid

The objective of this research is to develop models to assess potential benefits of cloud-based Smart Dual Fuel Switching System (SDFSS) of the residential hybrid HVAC system of electric air source heat pump (ASHP) and natural gas furnace/boiler (NGFB) for simultaneous reduction of energy cost and greenhouse gas (GHG) emission. It will entail detailed modelling, […]

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Innovation in Tax Filing: Identifying Barriers and Increasing Access

Federal and provincial governments use the tax system to establish eligibility and deliver benefits and credits to low-income Canadians. Low-income Canadians experience increased barriers to filing their taxes and thus do not maximize available benefits. This is likely to have worsened as free in-person tax clinics closed due to the COVID-19 pandemic or only provide […]

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Design Energy Harvesting Circuit and its System-on-Chip Implementation

We have seen the acceleration of global warming in recent years. Green-energy powered electronic devices are more desirable. In this proposal, we propose to develop an energy harvesting circuit and implement it on a system-on-chip. The design goals are low-cost, user-friendly, and portable. By partnering with Hidaca Ltd., our ultimate goal is to have this […]

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