Current cancer immunotherapies, although highly successful, are complex to implement, costly, and only effective in small patient populations with specific cancer types. We propose to overcome these problems by developing small molecules to induce immunogenic cell death (ICD), a cancer cell death process that engages the immune system to recognize and eliminate cancer cells and […]

Current cancer immunotherapies, although highly successful, are complex to implement, costly, and only effective in small patient populations with specific cancer types. We propose to overcome these problems by developing small molecules to induce immunogenic cell death (ICD), a cancer cell death process that engages the immune system to recognize and eliminate cancer cells and […]

Nearly 70% of all drug candidates are not pursued for pharmaceutical development because they cannot be dissolved into solutions appropriate for human use. Cuprous Pharmaceuticals Inc. (CPI) recently discovered that some of these drugs could be dissolved in the presence of certain metal ions. Furthermore, a number of metal-drug complexes are more therapeutically active than […]