Development of a Dynamic Model for In Vitro DNA Ligand Selection

Aptamers are single stranded DNA molecules that due to their sequence bind to specific target molecules. The process for the identification of aptamers for a specific target involves exposure of a large number of random sequences to the target followed by selection of sequences that bind. This process requires several several selection cycles for success. […]

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Highly Sensitive and Specific Detection of Aflatoxin B1 Implementing Aptamers and Gold Nanoparticle Localized Surface Plasmon Resonance

  Rapid diagnostic tools represent a significant growth industry in agriculture. Current antibody based approaches have implicit limitations due to the cost and performance of the antibodies. The use of single stranded DNA (aptamers) as mimics of antibodies has the potential to overcome many of these constraints. A key disadvantage to the use of aptamers is […]

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