Crif1 : Protein expression, purification and crystallisation

Human Crif1 is a protein with multiple functions, playing important roles in embryonic development, cellular stress, cell cycle regulation and mitochondrial membrane integrity. CRIF1 is coined to play a regulatory role in the Bone Marrow microenvironment-induced leukemia cell cycle arrest possibly through interacting with CDK2 and acting as a cyclin-dependent kinase inhibitor. In this project, […]

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Enhancement of signal quality in Near Infra-Red (NIR) spontaneous Raman spectroscopy using coherent detection techniques for use in real-time cancer microsurgeries

Raman spectroscopy is a compound identification technique that can be used for real-time identification of cancerous tissues during surgery. The development and clinical translation of an intraoperative surgical-guidance instrument based on this technique is the main objective of ODS Medical, a Canadian startup. However, Raman signals are intrinsically very weak thereby requiring the measurements to […]

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Development of a Real Time Bioelectric BOD Sensor for Wastewater Effluent Compliance Monitoring

The necessity of cost-efficient and reliable wastewater treatment processes has increased in order to meet more stringent levels of environmental regulations, increased system reliability requirements and tightening operational budgets. To aid in meeting these operational goals, a strong market for low-cost, high-fidelity sensor technology that can relay real-time information to system operators on all aspects […]

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Visualization of TBI Multimodal Brain Imaging Data

The increased incidence of traumatic brain injury (TBI) and its potentially serious long-term consequences have enormous clinical, societal and economic impacts in Canada. Yet despite its relatively high prevalence, TBI is one of the least understood neurological injuries. Emerging evidence shows that the effects of TBI are not transient and may be associated with significant […]

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Looking at the Physical and Psychosocial Outcomes of an After-School Physical Activity Intervention for Children with Congenital Heart Disease

The research intern will be working with Sportball to offer one of their multi-sport after-school programs to children who are living with serious heart defects. Physical activity has many health benefits for children, and after-school programs are an effective way to increase daily physical activity levels. Children living with heart disease are a vulnerable group […]

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The Future of Mandatory Charging for Intimate Partner Violence: Status quo or alternative direction? Phases II and III

According to the Ontario Domestic Violence Advisory Council (DVAC, 2009), legislative responses to violence against women were introduced across Canada in the 1980s. These policies included provisions for mandatory police-laid charges against perpetrators of domestic violence. The DVAC report noted numerous unintended negative consequences of these policies and recommended an impact study which was never […]

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Games as Analogical Scaffolds in Teaching and Learning

Games have, in the last decade, become an important tool for teaching in both the education and business section. The application of games, and game mechanics, in these areas is often called gamification. The aim of this project is to explore how games can be used to create rich, first hand, experiences that can be […]

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Caractérisation de l’écoulement dans le rotor d’une maquette d’alternateur

Compte tenu de l’accroissement du besoin énergétique auquel le monde devra faire face dans les prochaines décennies, l’industrie de l’énergie tend sans cesse à améliorer le rendement et la fiabilité de ses équipements. Une des avenues envisagées est d’augmenter la puissance des alternateurs hydroélectriques existants, repoussant ainsi la construction de nouvelles centrales. Beaucoup de ces […]

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Construction of Sustainable Corporate–Community Relations and Social Acceptance of Major Projects

The rise of local corporate–community conflicts surrounding development projects represents a trend rather than exceptional events, highlighting corporate–community relations as a prominent strategic issue. Despite the emergence of these issues for businesses, civil society, and governments, we still have a limited understanding of the conditions necessary for building and maintaining good relations over a long […]

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Topological Network Analysis for Transportation and Water Management Systems

The main goal of this project is to develop a general set of computational solutions that could be used to prevent and manage emergency situations in transportation and water management networks by developing a monitoring and predictive model. This monitoring and predictive model will be based on topological data analysis (TDA) in a fashion similar […]

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