Docetaxel is a key chemotherapeutic agent for treating locally advanced or metastatic breast cancer, but its effectiveness is often hindered by metabolic inactivation from drug-metabolizing enzymes, leading to multidrug resistance (MDR). This study aims to investigate the anti-metastatic effects of combining kaempferol, a flavonoid known for its anticancer properties, with docetaxel in both 2D and […]

This project aims to design and evaluate shape-changing interfaces to facilitate the understanding of complex geospatial and migration datasets. Prior solutions offer a static or screen-based visualization that often fails to convey the multidimensional nature of these datasets in an engaging manner that, in turn, limits the users’ ability to navigate dynamic and contextual information […]

The performance and stability of flexible mechanical structures in fluid flow can be improved by imposing bending-torsion coupling. In these structures, a bending deformation induces a torsional deformation which can be beneficial for the performance and stability. For instance, flexible wings can be tailored in such a way to have large deformations and twist passively […]

The growing demand for high-performance computing (HPC), artificial intelligence (AI), and cloud applications is pushing traditional semiconductor technologies to their limits. This project advances silicon photonics, which uses light for faster, more efficient, and scalable data transmission, making it critical for next-generation computing and communication systems. Focusing on hybrid quantum light sources and nonlinear optical […]

This project will utilise an integrated multi-omics approach for glycosylation-based breast cancer subtype discovery. Glycosylation is the process whereby carbohydrate structures are conjugated to cellular proteins and lipids, and in doing so, determines their functionality. Glycosylation is dysregulated in cancer and incorporating the glycome in cancer research has led to deeper mechanistic insight. Combining glycomic […]

Ce projet de recherche vise à examiner l’usage des expressions référentielles en français du Canada et en français de France, en se concentrant sur le discours politique. On s’intéresse plus particulièrement à la questions de la référence vague (on, les gens…) et à la manière dont elles sont employées pour introduire des informations non factuelles […]

The proposed research project is a theoretical study on the group silencing of Indigenous communities and advocacy groups in South Africa and Canada. The aim is to look into the historical and current systems, mechanisms, and some seemingly innocent acts that silence Indigenous groups and their advocacy groups and shed light on the significance of […]

This project aims to explore how changes in the cytoskeletal network influence nuclear morphology in plants, focusing on transgenic Arabidopsis thaliana that overexpress the nucleoporin Nup136

This project explores the emotional and cultural dynamics of artificial intelligence (AI) development across four global sites—Canada, the UK, India, and the US—by examining how emotions shape decision-making, productivity, and well-being within distributed teams. Focusing on the workplace processes of a leading transnational AI firm, the research addresses critical industry challenges in managing intercultural collaboration […]

Cranes are essential equipment in construction sites lifting and moving heavy loads. Due to the large structure, accidents can lead to significant casualties and property damage. Studies shows crane accidents are due to human error and miscommunication, and identifying the person responsible is important for preventing future accidents. A large number of reports are generated […]

Cancer is the leading cause of death in Canada. Cancer patients suffer from the side effects (e.g., hair loss) of the chemotherapeutics, as they lack selectivity, killing both cancerous and non-cancerous cells. Thus, there is a need for more selective drugs. Cancer cells need sugar for fast growth, having high levels of glucose transporters to […]

L’objectif du projet est de reconstituer l’historique des feux à la Forêt d’enseignement et de recherche du Lac Duparquet (FERLD), dans la forêt boréale mixte de l’ouest du Québec, à partir des sédiments de deux lacs. Ces reconstitutions seront réalisées en identifiant et en mesurant les fragments de charbon de bois séquestrés dans les sédiments […]