Endogenous opioid peptides and prescription opioid drugs modulate pain, anxiety and stress by activating four classical opioid receptors (MOR, DOR, KOR and NOP). The laboratory of Immuno-Pharmacology and Interactomics has recently identified a new broad-spectrum opioid receptor: ACKR3/CXCR7, hitherto known as atypical scavenger receptor for chemokines. In contrast to classical opioid receptors, ACKR3 is a […]

La stagiaire développera des méthodes d’analyses de protéines liées à l’inflammation pour la détection de la réponse immunitaire suivant une infection à la COVID. Elle procédera à l’analyse d’échantillon, la production de rapports et possiblement à la rédaction d’article. Elle utilisera des techniques de résonance des plasmons de surface.

The detection and the forecast of recurrent patterns is of utmost importance in financial time series. For example, it is useful to predict the explosion of price bubbles in advance in order to mitigate the consequences for the society. This project constitutes a further development of an existing research project on bubble detection via unsupervised […]

We propose to characterize idiopathic hypersomnia (IH) sleep microarchitecture and identify clinically-relevant IH subtypes based on their microarchitecture through advanced EEG signal analyses . We will analyze 601 participants including 135 IH patients, 94 healthy controls, 223 subjects with narcolepsy and 149 patients with suspected IH but who don’t reach objective sleepiness criteria. Sleep microarchitecture […]

The current research project investigates Ontario’s implementation of SMRs over an initial 30-year period, allowing for consideration of Ontario’s current energy mix as well as approximately two generations of SMR installations. Using linear programming and IBM’s CPLEX ILOG Optimization software, the development of a model which may compare front line SMR designs with the province’s […]

Par l’analyse des pratiques en gynécologie obstétrique chez les médecins de famille québecois qui ont la possibilité du suivi de grossesse et de l’accouchement contrairement aux médecins généralistes français, je cherche à analyser les deux pratiques de soins en santé de la femme dans ces systèmes de santé différents. Le but étant de comparer afin […]

Over 90% of ocular medications are administered by eye drops despite multiple drawbacks including low bioavailability of the target therapeutic, systemic toxicity, and the requirement for using high doses due to the effective clearance mechanisms for drug in the eye. To increase the therapeutic efficacy of ocular medications, novel nanocarrier systems have been developed that […]

Plenty of conclusive evidence points to the association of meat consumption with negative environmental outcomes resulting in climate change. These findings show the importance of reducing meat consumption and developing efficient strategies such as production of meat alternatives to alleviate the associated environmental and health issues. However, the production of plant-based meat analogues that can […]

In nature, animals must make decisions about where to find food. Looking for food, however, exposes animals to the risk of being eaten by predators and forces them to compete with other animals for food. This combination of risk and competition is stressful, and animals respond by releasing hormones help them cope. Initially, a common […]

Building hybrid quantum devices that compose of systems with complementary advantages is a promising approach to develop next generation quantum technology. In particular, the hybrid systems that consist of long-lived matter qubit (e.g. defect centers) and highly controllable photons (e.g. microwave in superconducting resonators) have been suggested to be a versatile platform for realizing quantum […]

As developed nations such Canada and Japan realize their commitments of achieving net-zero emissions by 2050, hydrogen-based fuels such as ammonia will become more important. More effective technologies for “green” ammonia will need to be developed to ensure the sustainable supply of zero-carbon fuels for shipping and electricity generation. I propose to develop effective electrode […]

Mon projet de mémoire de recherche s’inscrit dans le champ de la traductologie et se veut une approche renouvelée des textes antiques par le biais de leurs traductions. Il s’agit donc de comparer plusieurs traductions en français de l’Énéide de Virgile et de l’Anthologie Palatine à l’aide d’outils numériques (il conviendra d’ailleurs de tester plusieurs […]