Multi-biomarker test for the management of acute cardiac transplant rejection

The high incidence of acute organ rejection following heart transplantation poses major problems for patients, clinicians, and the healthcare system. A major clinical challenge in this regard arises from the difficulty of accurately and efficiently diagnosing when organ rejection occurs. In Canada, the current approach to diagnosing acute rejection requires taking small pieces of the […]

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Multi-biomarker test for the management of acute cardiac transplant rejection – Year two

The high incidence of acute organ rejection following heart transplantation poses major problems for patients, clinicians, and the healthcare system. A major clinical challenge in this regard arises from the difficulty of accurately and efficiently diagnosing when organ rejection occurs. In Canada, the current approach to diagnosing acute rejection requires taking small pieces of the […]

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Development of an environmental impact assessment tool for sports events

Although there is growing awareness of the need for sports events to take account of their environmental impacts and be “greener”, few sports organizations comprehensively assess their environmental performance due to the lack of tailored methods and tools. Small events in particular have limited resources and would benefit from a simplified assessment approach that allows […]

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Development of a Raman probe for the on-line determination of pulp properties

Canadian northern bleached softwood kraft (NBSK) market pulps set standards worldwide for fibre strength, length, fineness and uniformity. These characteristics add unmatched strength and durability to finished goods, and this drives a high international demand for NBSK pulp. However, competition has increased the price-performance pressure on Canadian suppliers. The Canadian pulp industry must innovate to […]

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Blockchain for Recordkeeping: Understanding Contextual and Technical Considerations through an Archival Science Lens

This research project is drawing on a previous study into blockchain technology. We plan to take our findings into the real world to investigate the potential for the blockchain network to improve supply chain management systems. The research will involve identifying areas where blockchain technology can enhance supply chain management processes.We believe that blockchain processes […]

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Entrepreneurial Delegation

Many entrepreneurs have passions for their ventures because they regard the ventures as their babies. Hence they are willing to put in greater amounts of “sweat equity” even if this greater effort is not fairly rewarded. This feeling is elicited by the entrepreneur’s psychological ownership. Although some psychological ownership is beneficial for new venture survival, […]

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Validation and Development of Clinically Relevant Copper Complexes for the Treatment of Bacterial Infections

Nearly 70% of all drug candidates are not pursued for pharmaceutical development because they cannot be dissolved into solutions appropriate for human use. Cuprous Pharmaceuticals Inc. (CPI) recently discovered that some of these drugs could be dissolved in the presence of certain metal ions. Furthermore, a number of metal-drug complexes are more therapeutically active than […]

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Modeling Human Cell Phosphorylation Network

It is believed that defects in the human cell phosphorylation network are related to at least 400 different diseases such as Cancer, Alzheimer, and Diabetes. The goal of this research is to model the components of the cell phosphorylation network (e.g. kinases, substrates, phosphatases, and SH2-PTB domain proteins) and their interactions, and ultimately to build […]

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Developing a Lipid-Based System for Co-delivery of a Vaccine and Adjuvants

University of British Columbia and Amgen British Columbia (ABC) will collaborate to develop a safe and efficient lipid-based vaccine delivery system that can be used in laboratory animals to enhance the production of specific antibodies against difficult targets. These antibodies can be further screened and characterized for treating various diseases in humans.

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Shake Table Testing and Analytical Validation of a Reduced Scale Dam Considering Dam-Water Interaction

Hydropower dams are significant investments and their integrity affects many stakeholders. Failure of a dam results in catastrophic events which cannot be mitigated. Seismic evaluation and prediction of dynamic response of dams need in depth assessment which has always been challenging with complex dam-water-foundation interaction. Impounded water considerably affects the response of a dam during […]

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