To investigate whether IO alters skeletal muscle adiponectin sensitivity and the mechanisms involved. 1. We will use L6 skeletal muscle cells treated with iron to determine if excess iron leads to adiponectin resistance. 2. We will examine temporal regulation of i) NLRP3 inflammasome and ii) oxidative stress by IO and using gain or loss of […]

Glycerol, a byproduct from biodiesel production, is a low value chemical because of excessive supplies on the global market. Current market prices in the European Union is estimated at $300 US/tonne. Glycerol can be converted into higher value chemicals using chemical, thermal and biological processes. Chemical and thermal processes are disadvantaged because they normally operate […]

This qualitative study will explore the social impacts provoked by the toddler & children-targeted health promotion program “Happy Smile” in small urban areas (state of São Paulo- Brazil). Mothers experiences within the program will be collected by the MITACS student , who will conduct interviews, informal conversations, and discussion groups to explore their understanding of […]

Research shows that many business employees are disengaged with their work, leading to numerous negative outcomes such as reduced productivity and burnout. The use of creativity and intuition have been suggested as two potential avenues for resolving these issues. However, there is a lack of direction for how these concepts can be practically applied in […]

This project seeks to explore the historical relationship between disability, technology and society, with a focus on Canada, but with global applicability. Through rigorous secondary, primary, oral and archival research, the team will investigate historical instances of innovation, technological use and activism by and for people with disabilities, building relationships and conducting oral interviews with […]

This work focuses on generation a framework to employ a set of 3D coordinates, as the input dataset to the model, and generate the 3D heat map based on the 3D shape. The generated 3D heatmap aims to define the most probable areas for fault categories on the 3D surface. To develop such a system, […]

Hydrolysis lignins (HL) are a byproduct from acid or enzymatic biomass pretreatment processes such as the ones employed in cellulosic sugar and/or ethanol plants. They are mainly composed of lignin , unreacted cellulose and mono and oligosaccharides. These lignins are, to a great extent, covalently bonded to cellulose and/or hemicellulose to form lignin carbohydrate complexes […]

Hypernasality is a speech disorders that results from excessive sound coming through the nose during speech. A speaker afflicted with hypernasality may be perceived as sounding flat and monotonous because the nasal murmur masks the inflections of the fundamental frequency (Kummer, 2008). However, the masking of prosody by the nasal murmur has not been investigated […]

A large number of civil engineering structures in North America have long survived their expected service life. As they continue to age, there is a significant demand to minimize damage under severe environmental impacts such as earthquake. The main objective of this project is to develop and validate vibration-based monitoring and control strategies using modern […]

Simulation is being used increasingly to improve medical education by providing students and trainees with greater access and opportunity to learn critical skills without affecting actual patient care. To this end, OtoSim has developed a multi-user training platform and an otoscope tracking device. The multi-user training platform allows the trainee to self-learn while being electronically […]

The phonology of a second language (L2) is rarely acquired at a native level by adult speakers, both in terms of perception and production of non-native speech sounds. In the native language (L1), evidence for a close link between speech perception and production has been found, whereby perception affects production and vice versa. When exposed […]

Major depressive disorder (MDD) is a serious mental condition that often completely debilitates a client. MDD is typically treated with one of several currently available antidepressant medications. However, the response rate to any of these medications is only about 30%. Unfortunately, there are currently no means for a priori assessment of whether a specific person […]