Characterizing intracellular interactions of carcinoembryonic-antigen-related cell adhesion molecule 1-4L using high resolution microscopy

Preliminary work has shown that adding excess CEACAM1-specific antibody, 26H7, to hela cells expressing carcinoembryonic-antigen-related cell-adhesion moleule (CEACAM) 1-4L decreases CEACAM1-4L in the plasma membrane and shifts their surface expression from a monomer-oligomer mix to mainly monomers. A super resolution microscope will be used to co-localize CEACAM1-4L with 26H7 in order to determine the optimal […]

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Analysis Tools for Automated Rehabilitation Assessment and Progress Tracking

In this project, Cardon Rehabilitation and Medical Equipment (CRME) and the University of Waterloo (UW) will test the Automated Rehabilitation System (ARS) for lower body physiotherapy in a clinical environment. ARS provides the ability to measure the human pose during the performance of rehabilitation exercises and provide real time feedback. CRME and UW are interested […]

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Extending artificial intelligence in the operating room

Assessment of surgical data from an operating room is a complex process that may require significant resources such as expert input and advanced technology. Automation brings a considerable opportunity to greatly reducing these significant resource requirements – e.g., using computer vision software to detect clinically relevant actions during surgery. However, those detections should be interpretable, […]

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Combining cortical stimulation and ‘mirrored’ visual feedback to enhance recovery of upper-limb: a pilot study.

Stroke is one of the most prevalent neurological conditions worldwide, especially among the elderly. Motor impairment is one of the main disabilities associated with stroke. The ability of training and physical activity to restore motor function after neural injury has long been appreciated. Nevertheless, even with intensive task-specific training and physical activity, 15–30% of patients […]

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DESIGN OF A NOVEL HEAT EXCHANGER TEST RIG

Heat exchangers, used in building heating, ventilation and air conditioning (HVAC) systems to transfer heat from hot to cold fluids, are designed to operate under ideal conditions. However, in practice operating conditions may vary with ambient temperature or humidity. HVAC system efficiency can be improved significantly if fluid flow rates are adjusted in response to […]

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Twisted foldings and double moment graphs

Schubert calculus is a well-established area of modern geometry that studies configurations and intersections of linear subspaces. Since its invention more than a century ago, it became one of the fundamental tools in different areas of mathematics, physics and computer science that deal with solving various types of linear equations. A typical question which is […]

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Optimization of Wastewater Treatment anaerobic digestion processes.

This project will test a variety of operating conditions used in anaerobic digestion (AD) in wastewater treatment (WWT) plants. The purpose is to identify optimal conditions for AD treatment process. Optimization of AD process would increase production of biogas for production of renewable energy, increase yield of bio-products for agriculture use, reduce WWT plant operating […]

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Scaling simulations in population health via machine learning

Computer simulations provide a safe alternative to taking a trial-and-error approach in the real-world. If a simulating intervention is found to be inefficient or even harmful, then it can be canceled without causing harm to real individuals. Consequently, simulations are increasingly sought after for complex social problems such as homelessness and the spread of the […]

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Detecting Company-Specific Purchase Evidence from Twitter Posts

Delphia’s business model revolves around generating insights for investing firms that allow them to make better trading decisions. It has been shown that detecting when Twitter users post about recent or future purchases has the potential to increase the accuracy of company sales forecasts, which in turn can inform stock trading strategies. This internship project […]

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Intelligent Character Recognition (ICR), Optical Character Recognition (OCR) and machine learning based corrections of data transcription from scanned business documents

SS&C processes more than 80% of financial scanned and faxed documents in the US and requires large amount of manual labor in order to map information from a document into another form. Advances in neural networks applied to computer vision have produced text detection and recognition that nears human performance. This project will be leveraging […]

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