A study on the application and mechanism of action of the lichen Umbilicaria muhlenbergii fractions on osteosarcoma and chondrosarcoma cells as a promising anticancer source

The purpose of this study is to determine the effect of the lichen Umbilicaria muhlenbergii fraction(s) on osteosarcoma and chondrosarcoma cells. MTT assay will demonstrate the activity of these fraction(s) against cancer cells. Appoptosis and inhibition growth analyses will be examined. The following objectives in the allocated time of five months (June 1-October 30, 2019) […]

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Needle segmentation from 3D ultrasound images

In this project I propose to develop a robust and efficient needle segmentation method, which will be used to localize and track the needle in three-dimensional (3D) ultrasound (US) guided focal ablation therapy. 3DUS guided biopsy and minimally invasive therapy involves guiding a needle into the lesion for biopsy (removal of tissue for pathological examination), […]

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Impact of Open Banking on Canadian Financial Transaction Platforms

Open banking systems have slowly migrated throughout the world, they are already implemented in Australia and Great Britain. An open banking system allows financial institutions to communicate directly with one another without the need of a central payment processing or clearance platform. As Canada turns to open banking in the future, payment processing platforms’ product […]

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Archival Research and Accessioning for the CSCE National History Committee

The proposed research project will determine the significance of and catalog historic papers and documents held by the National History Committee (NHC: established 1983) of the Canadian Society for Civil Engineering (CSCE: established as the Canadian Society of Civil Engineers in 1887). These records have been rather haphazardly stored by various Chairs of the NHC […]

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A personalized approach to the treatment of malignant melanoma: An economic evaluation of ipilimumab

Malignant melanoma is an aggressive form of skin cancer that is generally fatal if untreated. Approximately 10-20% of patients treated with ipilimumab may experience significant long term survival benefits. However, a UK agency recently recommended against public funding for ipilimumab on the grounds that no biomarkers have been discovered to identify the small group of […]

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Numerical simulation of dehydration of heat-sensitive shrinking materials

Description: During drying most real materials shrink depending on moisture content, physical structure and sometimes the rate of drying. Moisture and temperature dependent transport properties (such as moisture diffusivity, thermal conductivity etc.) that control the drying rate change significantly with the shrinkage of the product. A two-dimensional liquid diffusion model will be developed in MATLAB […]

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Resolving membrane protein dynamics and self-association characteristics by fluorescence fluctuation analysis

This project aims to exploit an analysis of cellular and molecular dynamics which focuses on understanding protein-protein interactions in living cells. It will focus on the development and application of a suite of novel single molecule super-resolution imaging strategies that will address fundamental questions surrounding how the association of specific membrane proteins drives localization and […]

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Using Machine Learning to Decipher Controls Water Quality

Water in the United States is a valuable resource. It is used from everything from drinking water to tourism. However, by the 1970s, many rivers and coastal areas were severely degraded from decades of using water to assimilate pollution. After billions of dollars spent and decades of effort on all levels of government, the increasing […]

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Quantum Optical Experiment to Understand Black Holes

Black holes are very intriguing astronomical objects. They do not emit light, so we can only get indirect evidence about their existence. When it comes down to understanding how they change in time, things get more complicated. Stephen Hawking argued that black holes have a finite lifetime. The question that arises then is, what happens […]

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