The purpose of this project is to ultimately decrease the likelihood of permanent sedentary lifestyles for at risk individuals. This includes overweight and obese men and women who are at risk of chronic diseases, and are in danger of excluding themselves permanently from active lifestyles. By developing and testing individualized behavior changing methodologies, this project […]

Personalized cancer therapy has immense potential to improve clinical outcomes of cancer patients because it tailors therapeutic treatment to each patient. To realize the promise of personalized medicine, there is an urgent need to develop new tumour models in the lab that can be easily tested, and also accurately represent responses of the original tumour. […]

Tumor-associated blood vessels are a major component of the tumor microenvironment because of their important role in supplying the tumor cells (TC) with nutrients and being the border for metastatic spread. Endothelial cells (EC) of blood vessels communicate with TC through direct interactions via Notch signaling. Our group could show that activated Notch1 receptors are […]

A multiple-systems theory of category learning proposes that an explicit, verbally-mediated system learns rule-defined (RD) categories categorization rules, and a procedural, nonverbal system learns new non-rule-defined (NRD) categories for which there is no easily verbalizable rule. Executive Function (EF) is a broad term that brings together cognitive processes like selective attention, inhibition, and reasoning, plays […]

People have to constantly adapt the way they move to achieve their daily goals. For example, an individual needs to use more force when walking through water than on dry land, and further adapt the direction of those forces if the water develops a current. Similar adaptations are needed when wearing a new pair of […]

How urban residents perceive and value nature within our cities shapes how we manage it for current and future generations. Given the diversity of perspectives and beliefs brought to bear on an urban system, we can expect that not everyone will enjoy nature the same way, or for the same reasons. If democracy is our […]

The research aims to compare and contrast the integration and ‘belonging’ of newcomers in Canada and Germany through following research questions: • Canada is considered to be a “settler colony”, and Germany an “ethnic nation”. How does this affect their immigration policies and integration of newcomers? • How do the newcomers identify themselves in these […]

Photosynthesis and respiration are major processes that influence the carbon cycle and will be impacted by future changes in precipitation. Short-term exposure to drought can decrease photosynthetic rates and growth, but plants can acclimate and adjust to water deficits over the long-term by changing their leaf physiology. The rate of acclimation may depend on nitrogen […]

Formal verification involves with proving properties about a system to make sure that the system is not free of bugs. There are two main methods for verification which are called model checking and theorem proving. Most current approaches to systems biology rely on model checking. Model checking is more automatic but not as general and […]