Atlas-based Attenuation Correction for PET/MRI

Positron Emission Tomography (PET) images need correction for the loss of photons. This

loss, or attenuation, is due to interactions with patient tissues. Corrections are currently done

with X-ray Computed Tomography (CT), however we are proposing a method whereby

Magnetic Resonance Images (MRI) are used. This will be done by creating an attenuation

map (?-map). The construction of ?-maps can be divided into two categories, patient specific

?-maps by MRI segmentation, and registration of a predefined atlas to an MRI. Challenges

with the former include object truncation, and reliance upon heuristics to transform an MRI

into a u-map. The latter technique can overcome these challenges, but relies upon the

selection of an atlas that is adaptable to a patient population. We will evaluate three

strategies for constructing an atlas suitable for whole-body PET/MRI. We will then compare

the performance of these methods with MRI segmentation-based and the gold-standard CTbased

methods.

Faculty Supervisor:

Stewart Gaede

Student:

Partner:

Multi Magnetics Inc

Discipline:

Engineering

Sector:

Professional, scientific and technical services

University:

Western University

Program:

Accelerate

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