Influence of walking speed and trunk sway on collision avoidance with a virtual human

During human navigation, vision plays a key role in efficiently guiding movements towards a goal by taking into account the interaction between the environment and the observer. Collision avoidance is comprised of two main aspects: visually perceived information, and behavioral adaptations. Previous research has demonstrated that humans alter their collision avoidance behaviours depending on situational […]

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Development of a biosensor for high-throughput screening of novel ezrin inhibitors for treatment of metastatic breast cancer.

Treatment of metastatic breast cancer is often unsuccessful and lead to 5000 deaths in Canada each year. Therefore, there is an unmet need for new drugs for prevention and/or treatment of metastatic disease. Ezrin is a protein marker commonly over-expressed in metastatic breast cancer. Preclinical studies show that blocking ezrin can significantly reduce metastasis in […]

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Transactive Electric Distribution System

Electric power distribution systems physically connect the newer active transactive energy (TE) elements such as energy storage, demand response, electric vehicles, and renewables to customer loads and electric supply from the transmission system. The proposal outlines a Transactive Electric Distribution System (TEDS) framework which enables the creation of a robust distribution system market in Canada […]

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Mineralogy and Shock Effects in Martian Regolith Breccias

In Martian history, asteroids have continuously collided with Mars. The catastrophic activity (impact) can produce high pressure, and finally affected properties of minerals in meteorites, which means the minerals were shocked. The force of impact for ejecting Martian meteorites can be 60 GPa, about 600,000 times of the atmosphere pressure on Earth surface. When the […]

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Stereoretentive-Enantioconvergent Catalysis: A New Concept in Asymmetric Synthesis

This project will experimentally establish a completely new method for accessing enantiopure materials starting from racemic substrates: stereoretentive-enantioconvergent catalysis. The ability to synthesize chiral molecules in enantiopure form is vitally important, most recognizably for the pharmaceutical industry. This is because the molecules of life are chiral (e.g., D-sugars and L-amino acids) and enantiomers often interact […]

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Examination of beneficial effects of copper fabric on cardiometabolic status, and mechanistic role of gut microbiome

Copper has long been proposed to have important biological properties. Designed to deliver the health benefits of copper, CuTEC yarn is a USPTO|EPO patent pending, bio-engineered copper-based yarn that can be produced as products such as clothing and mattress ticking. Although many believe in the positive properties of copper for well-being, many remain retiscent to […]

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Training the next generation of applied conservation biologists: research to aid Ontario’s first successful re-introduction of an endangered butterfly

The Mottled Duskywing is an endangered butterfly species in Canada. In order to reverse the decline of this species, research is required to fill in knowledge gaps regarding the species biology and life history. There are currently no data available on population size, survival rates of adult or juvenile life stages, dispersal, or optimal habitat […]

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Preparation of Mesoporous Oxides for Electrochemical Applications

Electrochemical technologies, such as fuel cells and electrolysers, could play an important role in the attempt to diversify the energy market. These devices can be used to produce clean, renewable energy and fuels. However, the technology cost is still far too high, preventing their large-scale implementation. A significant portion of the production cost comes from […]

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Off-Design Engine Modeling for Steam Turbines

Safely prolonging the life cyle of turbomachinery components, which would be replaced through scheduled overhauling, not only reduce the costs of operation but may also contribute to better sustainability of the life cycle management. XactLIFE is a prognostic software developed by LPTi (Life Prediction Technologies Inc., Ottawa, ON) to predict the life cycle of turbomachinery […]

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The physics of Boltzmann machines

Artificial Neural Networks are powerful tools used in the field of artificial intelligence. Inspired by the human brain, they have shown very good results in certain tasks, such as image classification and even in the generation of new images. The problem with neural networks is that we do not understand why they are working so […]

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Evaluating Adolescent Rickets in the Netherlands in the 19th Century

The proposed research aims to use non-destructive MicroCT analysis to investigate the levels of adolescent rickets and potential gender differences in the occurrence of the condition in two 19th century communities, Beemster and Hattem, in the Netherlands. In paleopathology, patterns of rachitic changes are well recognized in individuals that died during infancy and early childhood, […]

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