L2M-Free Flow Counterflow Gradient Focusing

Our project focuses on improving protein purification using a novel continuous separation method; Free-Flow Counterflow Gradient Focusing (FF-CGF). Traditional purification methods are slow, inefficient, and result in high sample loss, making it difficult for industries like pharmaceuticals and biotech to recover valuable proteins. Our technology offers a faster, more efficient alternative without the need for […]

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Developing Technetium radiochemistry to assess bisphosphonate-antibiotic conjugate biodistribution

The effective antimicrobial treatment of bone infections / osteomyelitis are often hampered by the secretion of beta-lactamase enzymes that inactivate the beta-lactam ring of otherwise effective penicillins and related antibiotics. To neutralize enzyme activity, beta-lactam antibiotics will often be co-administered with beta-lactamase inhibitors, such as Tazobactam. However, the systemic introduction of beta-lactamase inhibitors may not […]

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L2M – Commercialization of Natural Polymer-Based Wound Dressings

In collaboration with the Lab2Market Validate program, our goal is to transition our natural polymer-based wound dressing from the lab bench to commercial scale. Designed specifically for individuals with chronic wounds and fragile skin conditions, our hydrogel-based dressing aims to fill a critical gap in the market. Through the program, we seek to deepen our […]

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Artificial Intelligence/Machine Learning Application in Formulation of Novel Material Compositions and Visualization Design for Intensive Outreach and Education for Denture and Anti-snore Devices

Denture assemblies are oral appliances or prosthetic devices to replace missing teeth and restore oral function, speech, and aesthetics. The dentures market is driven by the senior population and demand, which is expected to grow by 68% in the next 20 years according to the Canadian Institute for Health Information. This demographic also often suffer […]

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L2M-Cell-fish Meats (cell-based Atlantic salmon, Atlantic cod, Atlantic wolfish, Sablefish, and Halibut burgers)

The Cell-fish Meats (cell-based Atlantic salmon, Atlantic cod, Atlantic wolfish, Sablefish, and Halibut burgers) project is aimed at starting a pilot project of lab-grown meat production from fish cells for human consumption. The targeted fish species are either expensive or difficult to access to the general public although they are some of the most popular […]

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Targeting bacteriophage delivery of reprogramming transcription factor gene(s) to astrocytes in CNS by Intelligent Phagemid-Assembled Gene Expression (iPhAGE) technology

This project aims to develop a method for delivering reprogramming transcription factor genes to astrocytes in the central nervous system using Intelligent Phagemid-Assembled Gene Expression (iPhAGE) technology. By constructing specific gene blocks and fusion helper plasmids, synthesizing iPhAGE DNA, and purifying iPhAGE preparations, the project seeks to enhance transfection efficiency and assess immune responses and […]

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Human cellular models to test lipid nanoparticle potency for mRNA

mRNA vaccine technologies came to the forefront of public health during the recent global pandemic and this technology also has great potential for other therapeutic approaches. These vaccine platforms require that the mRNA be encapsulated by fat molecules into structures called “lipid nanoparticles”, and the specific chemical formulations of the mRNA and fats determine the […]

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Co Operation Student – Deep learning applications in multispectral retinal imagery

The internship opportunity involves active participation in an agile AIS AI team dedicated to advancing the DeepMSI AI product. The intern will engage in impactful research under the AI team lead, focusing on refining core AI algorithms with a special emphasis on multispectral retinal image processing and deep learning. The objectives include exploring advancements in […]

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Molecular Standards for AUC Validation and GMP Practices

The discovery of CRISPR-based gene therapy methods using viral vectors, and SARS-CoV-2 vaccines based on lipid nanoparticle formulations has revolutionized the field of personalized medicine, and promises revolutionary applications for curing cancer, genetic disorders, and other diseases on the molecular level. To facilitate the validation of new therapies, biopharma companies use analytical ultra-centrifugation (AUC) to […]

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