L2M Launch- Vrit; A handheld bioprinting platform for treating severe skin wounds.

This project supports the commercialization of INSITE (In Situ Tissue Engineering Bioprinting System), a handheld bioprinting platform developed in the Guenther Lab at the University of Toronto. INSITE enables point-of-care delivery of personalized bioinks directly into skin wounds, offering a novel, autograft-free alternative for treating full-thickness burns and chronic wounds. Current gold-standard treatments rely on […]

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L2M – The design and fabrication of inert meso- and micro-porous PEEK membranes

This project aims to help bring a new type of filtration membrane—made from a strong and reusable material called PEEK—to the market, specifically for use in making biopharmaceutical drugs. The main goal is to understand the current market, talk to companies and other key stakeholders to identify their specific needs, and develop a clear plan […]

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L2M – BioThera Solutions

Our project aims to revolutionize the anti-aging skincare market by developing a breakthrough delivery system that enhances the absorption of active ingredients at the cellular level. Traditional skincare products often fail to penetrate deep enough to provide lasting results, leaving consumers with temporary fixes. By leveraging innovative biotechnology, our solution ensures more profound skin rejuvenation, […]

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L2M – Chase Biotherapeutics: Breaking barriers towards clinical translation of ChASE37-AR for stroke recovery

Stroke is a leading cause of disability, affecting 880,000 Canadians, with 109,000 new cases annually and no approved therapies for neuroregeneration. Current standard of care for ischemic stroke includes acute thrombolysis and/or thrombectomy to restore blood flow to the injured tissue, yet these treatments are time sensitive and only apply to specific stroke etiology, leaving […]

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L2M-Free Flow Counterflow Gradient Focusing

Our project focuses on improving protein purification using a novel continuous separation method; Free-Flow Counterflow Gradient Focusing (FF-CGF). Traditional purification methods are slow, inefficient, and result in high sample loss, making it difficult for industries like pharmaceuticals and biotech to recover valuable proteins. Our technology offers a faster, more efficient alternative without the need for […]

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Developing Technetium radiochemistry to assess bisphosphonate-antibiotic conjugate biodistribution

The effective antimicrobial treatment of bone infections / osteomyelitis are often hampered by the secretion of beta-lactamase enzymes that inactivate the beta-lactam ring of otherwise effective penicillins and related antibiotics. To neutralize enzyme activity, beta-lactam antibiotics will often be co-administered with beta-lactamase inhibitors, such as Tazobactam. However, the systemic introduction of beta-lactamase inhibitors may not […]

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L2M – Commercialization of Natural Polymer-Based Wound Dressings

In collaboration with the Lab2Market Validate program, our goal is to transition our natural polymer-based wound dressing from the lab bench to commercial scale. Designed specifically for individuals with chronic wounds and fragile skin conditions, our hydrogel-based dressing aims to fill a critical gap in the market. Through the program, we seek to deepen our […]

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Artificial Intelligence/Machine Learning Application in Formulation of Novel Material Compositions and Visualization Design for Intensive Outreach and Education for Denture and Anti-snore Devices

Denture assemblies are oral appliances or prosthetic devices to replace missing teeth and restore oral function, speech, and aesthetics. The dentures market is driven by the senior population and demand, which is expected to grow by 68% in the next 20 years according to the Canadian Institute for Health Information. This demographic also often suffer […]

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L2M-Cell-fish Meats (cell-based Atlantic salmon, Atlantic cod, Atlantic wolfish, Sablefish, and Halibut burgers)

The Cell-fish Meats (cell-based Atlantic salmon, Atlantic cod, Atlantic wolfish, Sablefish, and Halibut burgers) project is aimed at starting a pilot project of lab-grown meat production from fish cells for human consumption. The targeted fish species are either expensive or difficult to access to the general public although they are some of the most popular […]

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Targeting bacteriophage delivery of reprogramming transcription factor gene(s) to astrocytes in CNS by Intelligent Phagemid-Assembled Gene Expression (iPhAGE) technology

This project aims to develop a method for delivering reprogramming transcription factor genes to astrocytes in the central nervous system using Intelligent Phagemid-Assembled Gene Expression (iPhAGE) technology. By constructing specific gene blocks and fusion helper plasmids, synthesizing iPhAGE DNA, and purifying iPhAGE preparations, the project seeks to enhance transfection efficiency and assess immune responses and […]

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