This project between McMaster University and Carbon Upcycling Technologies (CUT) aims to commercialize sustainable agricultural products made from captured CO2. The team will assess markets for sprayable clay–polymer coatings that protect crops from UV damage and clay-based soil conditioners that improve water and nutrient retention. The outcomes will guide pilot partnerships and help CUT scale […]

This project explores how different processing methods affect the nutritional quality and health benefits of proteins from lupin, a sustainable legume crop. Lupin is rich in protein, environmentally resilient, and cost-effective to produce, making it an attractive alternative to meat and dairy proteins. However, the way proteins are extracted and processed can strongly influence how […]

Nucleic acids such as DNA and RNA offer exceptional opportunities to fight against infectious and genetic diseases. To use nucleic acids effectively in a clinical setting, one needs to use effective delivery vehicles that can deliver the nucleic acids into the diseased cells. This project will develop effective delivery systems for this purpose. The delivery […]

mRNA vaccine technologies came to the forefront of public health during the recent global pandemic and this technology also has great potential for other therapeutic approaches. These vaccine platforms require that the mRNA be encapsulated by fat molecules into structures called “lipid nanoparticles”, and the specific chemical formulations of the mRNA and fats determine the […]

Calcific tendinopathy (CT) is a staged, reactive process where pre-calcific changes are followed by a calcific phase (formative, resting, resorptive) and by post-calcific remodelling in which hydroxyapatite-like deposits form and quite often resorb spontaneously. CT is most prevalent in the neck, foot and hip and within the foot. The Achilles is a well-documented site of […]

The mission of PI16 Therapeutics is to improve skin health for the ~4 million Canadian’s suffering from long-term skin diseases, including clinically dry skin, chronic wounds, and severe burns. PI16 Therapeutics aims to produce skin solutions for these individuals by genetically engineering naturally occurring stem-cell like fibroblasts that express the gene Peptidase Inhibitor 16 (Pi16) […]

Ce projet vise à valoriser les résidus lignocellulosiques en créant des biocomposites imprimables en 3D dans une démarche de développement durable afin de capturer le dioxyde de carbone (CO2). L’acide polylactique (PLA), un polymère biodégradable issu se ressources renouvelables, est associé à du biochar produit à partir de résidus forestiers par pyrolyse, et du tanin, […]

This project focuses on developing advanced bioinks enhanced with tiny filler materials to improve 3D bioprinting for tissue engineering. By creating stronger, more printable, and biologically compatible materials, the project aims to help the partner organization advance regenerative medicine technologies. This will support the development of new personalized medical treatments and open up commercial opportunities […]

Le cancer touche en moyenne deux canadiens sur cinq, et chaque personne atteinte du cancer a une chance sur quatre d’en mourir. La recherche contre le cancer est l’une des plus actives dans le monde, et des traitements sont déjà mis à la dispositions des malades. Mais tous les cancers ne sont pas encore curables […]

Secreted protein acidic and rich in cysteine (SPARC) is a protein that is more produced by athletes (muscles) compared to sedentary individuals. We have previously shown that this protein is responsible for some exercise-induced effects, its injections also produce exercise-like effects, and its decrease/absence speeds up ageing. Therefore, SPARC could be an exercise substitute – […]

We are developing a promising new technology based on extracellular vesicles (EVs, often referred to as exosomes), which are natural delivery vehicles produced by cells. These tiny particles have the potential to transform how we treat diseases by delivering therapeutic ingredients directly to where they’re needed in the body. To bring this technology to market […]

This project focuses on developing innovative, biocompatible microrobots for targeted drug delivery, particularly in cancer treatment. By integrating smart hydrogels with magneto-active properties, these tiny robots can navigate the body and deliver highly precise chemotherapy drugs, reducing side effects and improving patient outcomes. Advanced 3D microfabrication techniques, such as two-photon lithography and digital light processing, […]