Functionalized adsorbent for simultaneous removal of heavy metal ions and ciprofloxacin

Ciprofloxacin (CIP) is a broad-spectrum antibiotic, frequently detected in different environmental compartments, which may contribute to antibiotic resistance occurrence. Another group of the contaminants, widely present in water and soils is heavy metal ions (HMI), like mercury, lead or cadmium. They are known to have toxic or poisonous effect on living organisms, including humans, even […]

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AI Techniques to Explore the Relationship Between Structural and Function Brain Connectivities

It is not fully understood how structural brain connectivities give rise to functional brain connectivities. The objective of this project is to apply Deep Learning and Machine Learning techniques to explore the complex relationship between structural and functional brain connectivities and accurately describe this important structure-function relationship. A linear brain dynamic network model will be […]

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Array Aspect Ratio Effect on Reversible Fibrillar Adhesion

Many small insects and creatures utilize reversible adhesion to vertically scale up walls and surfaces. The adhesion mechanisms are reliant on the tip geometry of highly dense fibrillar arrays as opposed to surface chemistry. The arrays can switch between high strength and completely non-adhering states. I will be investigating the role of array aspect ratio […]

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Dietary regulation of tissue circadian clock function in mice

The 24-hour light-dark cycle dictates the organization of life in most species on this planet. Internal timekeepers, so called circadian clocks, help to anticipate recurring daily changes and orchestrate the body’s physiological functions accordingly. In mammals, the core clock resides in the suprachiasmatic nucleus (SCN) and is synchronized by light. The SCN projects to several […]

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Chemical Genetics Approach: Function and Inhibitory Effect on Kinesins

This program is to analyze the regulation of cell cycle progression and the mechanism of chromosome segregation with regard to Kinesin5 and Kinesin8 families. Defects in these processes can result in the formation of aneuploid cells, a hallmark of many solid cancers. Thus, insights into the function and regulation of Eg5 and Kif18A (one protein […]

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Unravelling the sleepy brain: a neuroimaging study in central hypersomnolence disorders

Roughly 4-6% of the general population suffers from excessive daytime sleepiness. Central hypersomnolence disorders are characterized by incurable constant occurrence of this daytime sleepiness in combination with a disturbed sleep-wake cycle, resulting in severely impaired daytime functioning. Central hypersomnolence disorders are normally diagnostically divided in two types of narcolepsy and idiopathic hypersomnia. While narcolepsy type […]

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Confronting Colonialism at the Tropenmuseum: Understanding the Afterlives of Slavery

The research for this project will culminate in a final paper examining the Tropenmuseum’s new temporary collection Afterlives of Slavery, as a case study to consider efforts to transform the purpose and relevancy of museums. The exhibition, which recently opened in 2017, explores the Netherlands’ ties to slavery and colonialism, revealing how these histories continue […]

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Uploading of intercellular tension induces the directional translocation of PKC?

Endothelial cells( ECs) form the inner surface of blood vessels. If they break down, they may lead to vascular disease, heart failure,and high blood pressure. Endothelial cells(ECs) functions are regulated by permanent mechanical stresses such as shear stress and pressure from blood stream. When some cells are damaged, the adjacent cells are induced by them, […]

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MIM Plasmonic Bowtie Structures for Infrared Spectroscopy

Infrared (IR) spectroscopy is a diverse, powerful and nondestructive sensing technique amenable to a wide variety of applications. The sensitivity of IR measurements can be greatly improved by local electromagnetic field enhancements provided by nanoscale metallic structures. We propose a novel platform for enhanced IR spectroscopy, consisting of a bowtie structure composed of a nanoscale […]

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