Early Biomarkers for Prediction of Chemotherapy-induced RNA Disruption in Tumour Cells

Chemotherapy agents can induce the degradation of a molecule in tumour cells called RNA. We call this phenomenon “RNA disruption”. High tumour RNA disruption after about 1 month of chemotherapy predicts for complete tumour destruction and improved cancer patient survival. We and Rna Diagnostics, Inc. are using this knowledge to predict patient outcome from chemotherapy. […]

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The Pan-Canadian Immunoglobulin Database: Enabling Utilization Reporting and Personalized Treatment Using Data Mining Techniques for Immunoglobulin

Immunoglobulin (Ig) is a blood product that is used for people who either lack IgG antibodies or require immunomodulatory therapy for life-threatening autoimmune conditions. The use of Ig products continues to increase each year, at an average rate of 8%. The COVID-19 pandemic has introduced additional stress on the Ig supply due to a reduction […]

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Using Shared Mental Models to Improve Collaboration in Integrated Service Delivery Settings

Growing complexity of social needs, aligned with pressures for efficient and effective public services, has been met with calls for inter-professional, integrated approaches to societal problems (Henderson et al., 2020; Careau et al., 2018). Recent evidence has confirmed a positive relationship between shared mental models, and team/organizational performance (Evans & Baker, 2012). The purpose of […]

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Developing an Application to Facilitate Health Practitioner-to-Patients eConsultation

Despite the advances in medical science over the years, a great number of the world population still lacks access to basic healthcare. The health disparity between people in low resource settings and developed countries cannot be overemphasized. The disparity in health between developing and developed countries is evident in their life expectancy. However, the current […]

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Development of AI-assisted tools for enhanced clinical lymphoma PET/CT imaging

There are over 225,000 new cancer cases in Canada every year. Positron emission tomography/computed tomography (PET/CT) is the primary imaging modality for a range of cancer types. Various studies have established that determining size/volume, shape, and texture features of tumors from PET/CT images can help identify patients at high-risk of cancer relapse, or for whom […]

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Methane Assisted Catalytic Upgrading of Extra Heavy Crudes under Moderate Conditions

Vacuum residue (VR) is the heaviest part of crude oil accounting for a large proportion in modern refineries, while its utilization routes are generally of low efficiency and high energy intensity, and thus economically and environmentally unfavorable. Similarly, bitumen recovered from Steam-assisted gravity drainage (SAGD) process experiences high viscosity and density as well as high […]

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Étude de la compatibilité de l’utilisation des espèces Trichogramma brassicae et Trichogramma ostrinae

Deux espèces de trichogrammes parasitoïdes sont présentement utilisées pour lutter contre la pyrale du maïs, soit Trichogramma ostriniae, soit T. brassicae. Ce projet vise à connaître l’effet de l’utilisation combinée de ces deux espèces. Les deux espèces possèdent des écologies différentes notamment en ce qui a trait à la diapause. Notre hypothèse de travail sera […]

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Thrombosis Service Research

This research project will help build the foundation of thrombosis research within Newfoundland and Labrador with a focus on the Thrombosis Service at Eastern Health. It will inform clinical practice within the province and beyond.

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Development of a tele-health rehabilitation system to provide automatic assessment of patients’ performance, improve patients’ adherence and enable remote rehabilitation-Phase I

Poor physical recovery, especially in remote rehabilitation, is the problem that will be addressed in this project. This project is Phase I of development of Fun-exercise module. Fun-exercise system uses gamification to boost patients’ adherence to their prescribed home-exercises. To achieve this goal, Fun-exercise will use mentally stimulating and customizable games paired with a set […]

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Oxygen saturation targets in hospitalized children with bronchiolitis: A multi-centre cohort study

Bronchiolitis is one of the most common causes of infant hospitalization and the costs associated with it are large. Since active treatments are mostly ineffective for bronchiolitis, supportive management (including oxygen saturation monitoring) is the main focus of inpatient management. However, ideal oxygen saturation targets for infants hospitalized with bronchiolitis have not been established. This […]

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Advancing Post-Secondary Opportunity for Autistic Students

Using simplified language understandable to a layperson, provide a general, one-paragraph description of the proposed research project to be undertaken by the intern(s) as well as the expected benefit to the partner organization. (100-150 words) The project has been developed in concurrence with the Sinneave Foundation’s aim to improve outcomes in education, employment and housing […]

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