Construction d’une approche d’analyse de la liberté d’exploitation adaptéeaux produits biologiques

La presente recherche traite de l’evaluation des risques faisant obstacle a la liberte d’exploitation (FTO) d’un produit biologique, tel que levaccin XX d’influenza developpe par Medicago®. Elle correspond a la derniere etape du systeme de controle P.I. et a, notamment, pour objet d’identifier de nouveaux risques, mais egalement de mettre a jour taus les risques […]

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Apelin Analog Therapy as an Innovative Treatment for Cardiovascular Diseases

Apelin, an innate peptide, is a critical component of the apelin pathway, which is responsible for regulatory mechanisms of the cardiovascular system. Apelin is downregulated in patients with cardiovascular disease, therefore limiting the cardioprotective potential of the pathway. This project focuses on the optimization of a biological analog, able to withstand enzyme degradation with improved […]

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Automated Change Detection of Serial MR Images Using Compressed Sensing

We aim to develop a new algorithm to detect changes in serial MR examinations. Computer-based change detection system is an important tool to automatically process abundant information produced by imaging systems and assist physicians to identify clinically important changes in the images. Many existing methods are computationally costly. The emerging mathematical theory of compressed sensing […]

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The interplay between mental health, mental illness, sport culture, and athletic performance in Olympic and Paralympic sport

Mental health is increasingly being recognized as a key component of elite athletes’ overall functioning and sport performance. Globally, research on antecedents (e.g., sport culture) and consequences (e.g., athletic performance) of mental health and illness in elite athlete populations is growing. However, little is known about the relationship between mental health, mental illness, sport culture, […]

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Découverte d’antigènes spécifiques au cancer du sein

Le risque de développer un cancer du sein chez la femme au cours de sa vie est de 11%. Chaque année dans le monde, environ 1 675 000 femmes reçoivent un diagnostic de cancer du sein. D’ici 2020, le coût total des soins pour leurs patients atteindra plus de 2 milliards de dollars par an […]

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Exploring the economic impacts of Human-Centered Design in the context of a non profit organization

This exploratory research will seek to answer the primary question generally asked by many industry professionals- “how to evaluate the economic assessment of projects (using Human Centered Design (HCD) philosophy)”. This research will explore how to create an ROI/cost benefit analysis tool to measure economic impacts of the specific type of projects. This report will […]

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The development and feasibility/acceptability testing of an online mind-body wellness program for primary biliary cirrhosis

Persons with primary biliary cholangitis (PBC) have high rates of liver disease-related symptoms and poor health-related quality of life – amongst the lowest of all chronic liver diseases. Patients and the Canadian PBC Society have identified the need for self-care tools to manage symptom burden. Building upon a previously developed online wellness program for inflammatory […]

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Genetic susceptibility to renal cancer

Renal cell carcinoma (RCC), the most common type of kidney cancer, is characterized by heterogeneous tumor biology and clinical outcomes. Due to the indeterminate behavior of RCC and the absence of routine biomarkers, it is difficult to identify individuals at risk to develop RCC, and patients who are at high-risk of relapse. There are also […]

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The influence of absolute strength on metaboreflex activation

Premenopausal women typically have lower blood pressure responses to static exercise compared to age matched men despite similar relative exercise intensity. Some research attributes this difference to an innate effect of biological sex due to differences in metabolism and sympathetic transduction, but work from our lab shows that matching for muscle strength abolishes within and […]

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Stage de maîtrise dans le cadre d’un projet de recherche au Brésil

Le projet se déroulera à Fortaleza, une ville au nord-est du Brésil et fera partie d’un projet de recherche plus large portant sur la mobilisation communautaire en but de contrer la propogation de la dengue dans cette ville. De plus, le projet fera objet d’un stage de maîtrise et visera à évaluer les défis quant […]

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Optimization of Bioink Composition for Efficient Mesenchymal Stromal Cell Chondrogenic Differentiation in an Animal Component-Free Culture

Culture of cells in three-dimension (30) allows cells to interact with their surrounding and grow in all directions and behave in a manner that is more closely associated to how they would in vivo as long as their nutrient and environmental requirements are maintained. In this context, bioprinting offers an advantage over 20 cell cultures […]

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