Exploring and modeling human cognition through deep learning

Some of us recall our dreams very often, while other hardly ever remember them. The neuroscience of sleep and dream research is a thriving field with still many unanswered questions. Differences in brain network dynamics between individuals with high versus low dream recall rates, are still poorly understood. In this internship, we will address this […]

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Employing Raman Spectroscopy for monitoring a vaccine manufacturing process

Vaccine antigen production is a process that entails numerous variables. In order to have a consistent and robust process, monitoring of process parameters and controlling output variables within a certain range is the best practice. To accomplish this objective, analytical tools are used, on-line, off-line, at line. Real time monitoring of the processes is advantageous […]

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Probiotics Counteract Gut Microbial Dysbiosis and Long-Term Neural degeneration in Male and Female CD1

Changes in the intestinal microbial composition (dysbiosis) during development have an impact on the progression of neuro-inflammatory and neuronal degenerative disorders. Probiotics have been shown to reduce these effects. However, the current literature lacks research on intestinal dysbiosis during the maturation of the intestine and the brain and does not recognize the sexual dimorphism of […]

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Predicting 30-Day Risk of Hospitalization, Emergency Department Visit and Death Among Albertans Receiving Opioid Prescriptions Using Machine Learning Algorithms: A Prognostic Study

Prescribers rely on guidelines for appropriate use and prescribing of opioids. Currently, there are no risk prediction calculators available to quantify the risk of prescribing an opioid that uses a patient’s history and drug utilization pattern. Machine learning algorithms offer an opportunity to perhaps develop such a risk calculator as a result of the large […]

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Investigation of the Role of Host Proteins in the HIV-1 Envelope

While efficacious treatments are available for HIV, they require lifelong adherence and can have harmful effects over time. Therefore, developing novel treatments and a preventative vaccine remain critical. While most vaccine attempts to date have been largely unsuccessful, identifying new targets on the virus, may provide novel avenues for HIV vaccines and therapies. Integrin alpha […]

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Robot-Assisted Breast Cancer Surgery

Breast cancer affects 1 in 8 women during their lives and is the second-leading cause of female cancer related deaths. The ideal treatment is breast-conservation surgery during its early stage to remove the cancer while conserving healthy parts of the breast. With current resection methods, on average, one out of every three women undergoing breast-conservation […]

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Développement, implantation et étude des retombées de capsules vidéoorthophoniques sur l’autonomisation des personnes vivant avec la maladiede Parkinson

La maladie de Parkinson touche plus de 1,5% des personnes de plus de 65 ans et jusqu’à 90 % des personnes atteintes développent des difficultés à avaler ou à s’exprimer au courant de leur maladie. Ces difficultés nuisent aux relations sociales des personnes qui vivent avec cette maladie. Des thérapies en orthophonie peuvent aider à […]

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Unraveling the electrophysiological basis of auditory entrainment from a gender perspective

An important challenge in developmental psychiatric research is to understand which are the neural mechanisms underlying language acquisition and speech comprehension. Auditory entrainment is the mechanism by which the brain faithfully entrains electrophysiological activity to rhythmically modulated stimuli, and it is seen as the mechanism that the listening brain use to attune to acoustic regularities […]

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Eng/aging and HIV: Knowledge Exchange Between Administrative Data Project and Aging Individuals with HIV/AIDS in British Columbia

To an unprecedented degree in the history of HIV/AIDS, people with HIV/AIDS (PLHIV) are aging largely owing to the success of treatment. As a relatively new phenomenon, research on HIV/AIDS and aging is only just emerging, and remains largely epidemiological in focus. One leading epidemiological study called COAST comes from the B.C. Centre for Excellence […]

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Eng/aging and HIV: Knowledge Exchange between Older Adults Living with HIV and Big Data Researchers in British Columbia – Year two

To an unprecedented degree in the history of HIV/AIDS, people with HIV/AIDS (PLHIV) are aging largely owing to the success of treatment. As a relatively new phenomenon, research on HIV/AIDS and aging is only just emerging, and remains largely epidemiological in focus. One leading epidemiological study called COAST comes from the B.C. Centre for Excellence […]

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Probiotics to prevent the Progression of Non-alcoholic Steatohepatitis to Cirrhosis

As a result of increasing obesity, non-alcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease. Non-alcoholic steatohepatitis (NASH) is the pathogenic form of NAFLD and can progress to cirrhosis and need for liver transplantation. There is currently no Health Canada-approved therapy for the treatment of NASH. The intestinal microbiome has been […]

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Effect of probiotics on reducing diet-induced inflammation and atherosclerotic plaque formation in APoE-knockout mice

Diets which reduce carbohydrate intake and increase protein intake, such as Atkins diet, are popular and effective for weight loss. However, such diets may negatively affect cardiovascular health by increasing atherosclerotic plaque formation, and overall lead to higher mortality. Vuckovic and Bergdahl previously used mouse model that mimics spontaneous formation of atherosclerotic plaques in humans […]

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