ABHD6 as a novel drug target for obesity, non-alcoholic fatty liver disease (NASH) and cardiovascular disease (CVD)

Obesity, type 2 diabetes (T2D) and heart diseases have skyrocketed. Controlling glucose usage and insulin balance can substantially decrease the morbidity and improve the quality of life in affected individuals. Dysfunctional insulin action and energy balance in the body is associated with excessive non-adipose fat storage, particularly in the liver, and elevated circulating lipids, which […]

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Evidence-informed Planning and Evaluation of Community Transitions: Impact on Health and Quality of Life

St.Amant is an organization that offers services to support individuals with developmental disabilities. Many of St.Amant’s services are shifting to provide the most inclusive, supportive, community-based services with the intention of enhancing health, access to healthcare, and quality of life of persons served and that of their families and caregivers. One of the current service […]

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Development of an infrastructure for AAL technology data exchange to inform policy and governance guidelines

The UbiLab and the CSA Group are collaborating on the development of a roadmap for a data integration infrastructure that will enable Ambient Assisted Living technology to share data at a wider scale. The current technology landscape has resulted in manufacturers of Internet of Things and Ambient Assisted Living technologies generating siloed data that provide […]

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Testing of Cannabinoid Oil Extracts in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model of Multiple Sclerosis (MS)-Induced Neuropathic Pain (NPP)

The cannabinoid class of medications are widely used to treat disease or alleviate symptoms such as spasticity and pain associated with MS. However, the exact molecular mechanisms by which they exert their beneficial effects remain unknown. Recent research and clinical trials demonstrated that cannabinoids may not only alleviate the symptoms of MS, but may also […]

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Assessing the Utility of a Commercial Mobile EEG in Detecting Age-Related Differences in the Brain – Year two

The world is aging rapidly and healthy cognitive aging a major healthcare priority. Thus, a better understanding of how the brain changes with normal aging versus pathology is required. Advancements in wearable technologies may allow the assessment of brain function with greater ease, accessibility, and at a lower cost, as compared with traditional neuroimaging techniques. […]

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Image Analysis and Machine Learning for Digital Pathology Images

Histopathology is the study and examination of tissue slides under magnification and is the definitive diagnosis for many diseases including cancer. With the advent of whole-slide scanners and image management software systems, computational pathology tools can be created to measure disease in an efficient and objective manner. This is in contrast to the labourious and […]

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