High-Fidelity Data Converters for Medical Diagnostics

Diagnostic medical devices work by translating our vital signs, such as neuron electrical activity and brain waves, into digital data that can be manipulated by a computer. High-speed computer processing improves diagnoses by presenting the physician with a numeric or graphical readout of important features extracted from the signal. Often, the ability of computer programs […]

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Exploring the lived experience of survivors: The link between intimate partner violence (IPV) and traumatic brain injury (TBI)

Past research has established that a high percentage of women in violent relationships experience a traumatic brain injury (TBI), with one article estimating approximately 23 million women in the US living with a TBI from intimate partner violence (IPV) (Ivany & Schminkey, 2016). While previous research has focused on establishing the link between IPV and […]

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Wearable Sensors for Monitoring of Human Activities

Quantification of human standing balance provides unique insight into the integrity of the human sensorimotor system, including the identification of balance deficits in conditions such as mild traumatic brain injury (mTBI), stroke, and aging. While a number of high-cost instrumented balance quantification systems are available, they are primarily geared towards research settings. Novel technologies using […]

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CyTOF-based characterization and isolation of MDSC subsets

Myeloid-derived suppressor cells (MDSC) are an unusual type of blood cell that is able to potently turn off immune responses. These cells are not normally present in healthy individuals, when a tumour is present, MDSC can block clearance of the tumour by the body’s immune defenses. A better understanding of how MDSC shut down tumour […]

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SWAVE Ultrasound Elastography

Organ health is often tested today by biopsy, which involves placing a needle into the body and taking a small tissue sample for analysis in a lab. Researchers at the University of British Columbia invented a new technique to measure the health of tissue without a needle. This technique is called Shear Wave Absolute Vibro-Elastography […]

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Puissance Dys : projet-pilote préventif pré-scolaire utilisant des interventions éducatives intermodalitaires

Le présent projet de recherche au service de l’organisme Dysphasie-Estrie vise à encadrer la mise-en-place d’un tout nouveau projet-pilote pré-scolaire s’adressant aux familles de l’Estrie. L’Académie Puissance Dys est un service spécialisé en langage et apprentissage afin que les enfants développent le nécessaire pour réduire leurs écarts de développement et puissent assurer une transition réussie […]

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Advanced differential mobility mass spectrometry with electron capture dissociation for the characterization of therapeutic proteins

Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce […]

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Advanced differential mobility mass spectrometry with electron capture dissociation for the characterization of therapeutic proteins – Year two

Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce […]

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Pharmacogenetic Biomarker Discovery, Personalized Medicine, and Clinical Test Commercialization in Neuropsychiatry

Pharmacotherapy is one of the primary treatments for psychiatric disorders. Given the variation in individual response, and the current trial-and-error treatment, a more personalized approach is needed. The Mitacs Elevate postdoctoral trainee will gain direct experience with all aspects of using pharmacogenetic testing to personalize medication prescriptions for patients, and the commercialization of the test. […]

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Pharmacogenetic Biomarker Discovery, Personalized Medicine, and Clinical Test Commercialization in Neuropsychiatry – Year two

Pharmacotherapy is one of the primary treatments for psychiatric disorders. Given the variation in individual response, and the current trial-and-error treatment, a more personalized approach is needed. The Mitacs Elevate postdoctoral fellow project involves the use of pharmacogenetic testing to personalize medication prescriptions for patients, and the commercialization of pharmacogenetic testing. A main component of […]

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