The mechanisms by which high fructose consumption leads to hypertension

The main goal of this research project is to understand how the consumption of fructose can lead to the developement of hypertension. Hypertension is one of the most world spread health condition and a major risk factor for cardiovascular diseases, stroke and death. The high presence of fructose in the body, whether directly due to […]

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Processing and Preservation of Moringa oleifera

Examine the effects of different drying methods on colour and flavour compounds in Moringa oleifera leaves and drumsticks. The proposed hypothesis is that flavouring and colouring compounds of Moringa leaves and drumsticks are unstable and/or highly volatile during drying process. This exchange between the University of Toronto and the Tamil Nadu Agricultural University will explore […]

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Microclimate Modelling for Vancouver Neighborhoods

Extensive urbanized land surfaces, anthropogenic heat emissions, and lack of vegetation and tree cover contribute to the formation of distinct urban climates where warmer air and surface temperatures intensify outdoor heat exposure and thermal discomfort for pedestrians. To assess outdoor thermal comfort in urban environments, mean radiant temperature (Tmrt) is a commonly used indicator. The […]

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Development of a novel system to isolate vocal sources in crowded environments for individuals suffering from hearing deficits

Hearing aids are a common form of treatment for individuals suffering from a hearing impairment [1]. These devices work by collecting sound from the surrounding environment and amplifying that sound in the patient’s ear to improve hearing [2]. These devices work well under most conditions however, in noisy settings such as a busy restaurant, hearing […]

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Tagging and Auto-Captioning of Histopathology Scans for Diagnosis Assistance

Digital pathology uses modern scanners to capture high-resolution images from biopsy samples. Computer algorithms, especially artificial intelligence, can help in automatic searching for similar cases in the archive of hospitals and laboratories. Displaying similar images form the past patients, that have already been diagnosed and treated, can provide useful information to the pathologist to solidify […]

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Eastside Works: Information System Support and Evaluation

EMBERS Eastside Works (EW) is a new low barrier employment centre in the Downtown Eastside of Vancouver. EW helps people in the Downtown Eastside make connections to the world of work, earn income, and improve their livelihoods. The proposed research will work with EW to develop a database and information system that fits their needs, […]

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Antigen tracking of the DepoVaxTM-R9F cancer vaccine using MRI

Immunovaccine Inc. is developing cancer vaccines using the company’s DepoVaxTM vaccine technology. DepoVax is a patented formulation that displays excellent tumor control and provides a long lasting and specific effect. The way by which this vaccine exerts its effect is unclear but the translational team at Immunovaccine is determined to discover its mechanism of action […]

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Glucocorticoids and Oxidative Stress in Bipolar Disorder

This project is on understanding the biological processes that underlie Bipolar Disorder (BD). BD is associated with dysfunctional oxygen metabolism and energy production, leading to the excess production of reactive oxygen molecules, which damage or alter the function of brain cells. Because BD is also associated with increased stress response systems, the current study aims […]

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Linking Animals, Social Justice and Social work

Speciesism – discrimination by species – is recognized by some moral philosophers as a social justice issue. It is a problem for animals and humans alike since studies show that how we treat animals is related to how we treat each other and to public health. We aim to raise awareness of speciesism among social […]

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Developing statistical methods to discover genetic variants underlying longitudinal decline in lung function

COPD is a common inflammatory lung condition that is characterized by airflow limitation and symptoms of cough and shortness of breath. Globally, it affects 384 million people and is responsible for ~4-7% of all deaths. Longitudinal genome-wide association studies (GWAS) are needed to unravel the molecular determinants of dynamic quantitative traits underlying COPD, such as […]

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Development of the Feldan Shuttle platform / Amélioration de l’activité cytotoxique des cellules Natural Killer (NK) en utilisant une stratégie d’invalidation de gène(s) cible(s) par technologie CRISPR

Feldan Therapeutic developed the Feldan Shuttle platform, a breakthrough peptide-based delivery method that allows the introduction of foreign proteins inside cells. The Feldan Shuttle overcomes delivery obstacles in therapeutic context by providing a safe and highly efficient approach that is associated with low regulatory burden. The Shuttle platform can transfer active nucleases and transcription factors […]

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