A data visualization framework to leverage text and knowledge graphs

The goal of this work will be to explore different ways to visualize and interact with knowledge extracted automatically from very large heterogeneous document collections. This extracted knowledge will be in the form of a multi-attribute graph of extracted entities and relationships between them. These relationships will be associated with both temporal and spatial information. […]

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Endocrine and Paracrine Control of Spermatogenesis

The proposed project will investigate fish spermatogenesis in the seminiferous tubules of the testis. Specifically, it will look at the underlying endocrine and paracrine mechanisms that control the different phases of spermatogenesis, with focus on the spermatogonial phase, including the spermatogonial stem cells. This would include studying the in vitro effect of androgens on the […]

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Understanding the mediators of employee wellness in an activity-based workspace

Adoption of an activity-based workspace is rapidly increasing. Employees in activity-based workspaces do not have a set workstation. Instead, employees can choose from a variety of workstations (e.g. desks, lounge space, quiet offices) according to their needs. Despite increasing adoption, we know little about the impact of activity-based workplaces on employee wellness, satisfaction, and productivity. […]

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Rotator cuff tears: a covert source of shoulder disability (Prognostic value of patient’s demographic, clinical and genetic factors)

This study aims to develop a scoring system to screen the sub-clinical forms of rotator cuff tears and predict the tear progression. All the medical, genetic, work, and lifestyle backgrounds of individuals with rotator cuff defects (with and without symptoms) will be evaluated and a battery of manual tests and measurements will be performed to […]

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Exposure to Multiple Pesticides and Risk of Multiple Myeloma in Canadian Men

Multiple myeloma (MM) is the second most common hematological cancer in Canada, affecting an estimated 2,300 people in 2011. Farm work is most consistently associated with an increased risk of MM. Occupational exposure to pesticides has been linked to increased MM risk in Canadian and European studies. Previous investigations mostly focused on individual pesticide exposures, […]

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Contribution of Achilles tendon mechanics to torque steadiness of the intact limb of unilateral lower-limb amputees

Torque steadiness (TS) is the ability to maintain torque around a given target torque level and is representative of functional movement control. In unilateral lower-limb amputees, plantarflexor TS is reduced. The Achilles tendon plays a critical role in the required transfer of torque from muscle to bone to maintain TS. To-date, no study has investigated […]

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Structural design, molecular modeling studies and synthesis of novel pyrrolidine derivatives as ligand candidates to target alpha-7-nicotinic acetylcholine receptors focusing on Alzheimer’s disease.

Alzheimer’s disease (AD) is one of the most common types of neurodegenerative disorders and the development of an effective treatment remains a challenge for researchers today. The nicotinic acetylcholine receptors (nAChRs) which are closely related with AD, especially the alpha-7-nAChR, are involved in neuroprotective effects (effects which may result in the salvage, recovery or regeneration […]

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Validation and Usability Analysis for a Return to Work Software Platform

Benefit payments totaled 2.5 billion dollars for Ontario workplaces in 2015. The most common injury resulting in occupational lost time claims is a strain or sprain. These injuries indicate that despite massive efforts to reduce musculoskeletal injuries in Canadian workplaces, these issues are still a prominent source of disability and have an associated $2.5 billion […]

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Safe Harbour for Military, Veteran and Family Health Research Data

The Canadian Institute for Military and Veteran Health Research (CIMVHR), affiliated research partners at universities across Canada, and IBM Canada Ltd. have identified a significant and universal issue facing health researchers that applies to Canadian military, Veteran and family health (MVFH) research and health research for the Canadian population at large. Comprehensive and complete medical […]

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Translational Research in Visual Analytics for Personalized Health

Personalized health is increasingly gaining public attention in the media as the future of healthcare. Personalized health is the idea that medical treatment will be tailored to the individual based on their predicted response or risks of disease. Omics analysis, defined as the universal detection of different classes of biological molecules, has the potential to […]

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Using advanced analytics to develop a multimodal signature of concussion and post-concussive syndrome

Concussions are extremely common in deployment and in military and civilian activities (i.e. sports). Persisting symptoms that make up “post-concussive syndrome” (PCS) including headaches, balance difficulties, depression and anxiety can occur in 10-15% of cases. The diagnosis of concussion and PCS is currently based on a patient’s report of their symptoms and a physical exam. […]

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Modeling Oxygen Behaviour in Point-of-Care pO2 Devices

A mathematical model is to be developed that describes how oxygen can move in a point-of-care blood gas sensor. The sensor measures the partial pressure of oxygen in a blood sample. Oxygen can move throughout the cartridge by diffusing through the various materials that make up the cartridge. The extent to which the oxygen can […]

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