L2M – EPAID Technology: EPilepsy AI-Driven Technology

EPAID Technology: EPilepsy AI-Driven Technology aims to automate electrophysiological signal processing practice to assist clinicians in the treatment of epilepsy. We will partner with Springboard, who provides strategically positioned resources to Atlantic Canadian universities and colleges alike, helping them transfer both knowledge and technology into the private sector.

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L2M – Clinical Development of a Novel NanoString Assay Predicts Survival and Clinical Outcomes in Myelofibrosis Patients

Myelofibrosis is a chronic and life-threatening blood disease. There is a need for accurate risk stratification approaches to guide personalized medicine decisions for these patients. To address this need, we developed a non-invasive blood-based test that is cost-effective, scalable and accurate. Through the Lab2Market program we will explore the market and develop the business case […]

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Improved quality control of blood products using high throughput mass spectrometry coupled to machine learning approaches.

We will assess the quality and suitability of blood and blood-derived products using a fast and economical approach that combines measurements of molecules in the blood product identified by their weight and computational approaches to make sense of all the data generated. Normal blood products have thousands of small molecules in common. By monitoring a […]

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L2M- Remote Care: Empowering patients through Remote Self-administered Medical assessment.

“RemoteCare” is a novel initiative that empowers individuals to conduct part of their medical assessments independently via a user-friendly remote digital solution. By enabling self-assessments, it reduces physician workload, minimizes wait times, and ensures quicker access to medical assistance, especially in underserved areas. However, its progress hinges on gaining the trust of traditional healthcare providers, […]

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L2M- Unobtrusive Monitoring of Heart Failure via Ballistocardiograph

In Canada, heart failure (HF) has a 30-day re-admission rate of 17.6%. While patient care at home via follow-ups and self-management may reduce this rate, factors including physical fatigue and cognitive frailty delay follow-up visits and impair the patient’s ability to self-manage. An implantable solution such as CardioMEMS is available to monitor HF, however, its […]

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Targeted synthetic and biosimilar disease modifying antirheumatic drugs in pregnancy: Patterns of use among females with rheumatic diseases and outcomes

Our proposed research project aims to answer the overall question: how do new arthritis medications taken during pregnancy affect mothers and their children? Many types of arthritis strike in females during their childbearing years. Even though we now know more about the effects of arthritis drugs when taken during pregnancy, the picture is not yet […]

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Impact of early vaccination during influenza outbreaks

Vaccination is an important preventive measure against influenza infection during both seasonal epidemics and pandemic outbreaks. This research aims to understand the effect of early vaccination during influenza outbreaks. The objectives are to measure the effectiveness of early vaccination in terms of reducing disease burden (e.g., infection, hospitalization). We apply an important methodology, namely mathematical […]

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3D topographic acquisitions to avoid serial x-rays during scoliosis brace treatment

In this study, patients with idiopathic scoliosis followed at SickKids will undergo topographic analysis using the Momentum Health scanning application in addition to standard of care clinical evaluation and x-rays. The study period is 1 routine clinic visit followed by 3 months after. Patients will self-scan 1x/month at home for the following 3 months. The […]

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Mise au point d’un protocole d’impression 3D de comprimés d’hydroxyurée

L’hydroxyurée est un médicament utilisé pour prévenir les complications de l’anémie falciforme ainsi qu’en chimiothérapie d’appoint pour certaines leucémies. En pédiatrie, l’hydroxyurée doit toutefois être ajustée selon le poids de l’enfant, ses prises de sang et la toxicité perçue. Or, au Canada, seule la formulation de 500 milligrammes est disponible. Ainsi, nos hôpitaux et nos […]

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Comparing the risk of adverse events across different classes of biologics and comparable safety and efficacy of biosimilars versus originator biologics in inflammatory arthritis

Our proposed research project aims to answer the overall question: what is the actual risk of infections or cardiovascular events for patients with inflammatory arthritis that take novel arthritis medication (biologics) and how does it compare between different classes of these drugs, in real-world settings? As well as asking if the safety and effectiveness of […]

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